一种基于时间分辨荧光共振能量转移（TICT）的荧光探针，用于快速、特异性地检测硫化氢及其生物成像应用。
A TICT-based fluorescent probe for rapid and specific detection of hydrogen sulfide and its bio-imaging applications.
作者信息
Ren Mingguang, Deng Beibei, Kong Xiuqi, Zhou Kai, Liu Keyin, Xu Gaoping, Lin Weiying
机构信息
Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Biological Science and Technology, University of Jinan, Jinan, Shandong 250022, P. R. China.
出版信息
Chem Commun (Camb). 2016 May 11;52(38):6415-8. doi: 10.1039/c6cc00966b. Epub 2016 Apr 19.
By blocking the intramolecular twisted internal charge transfer (TICT) process, we designed and sythesized the first TICT-based fluorescent probe for hydrogen sulfide. The new probe exhibits high selectivity, good membrane-permeability and is suitable for visualization of exogenous and endogenous hydrogen sulfide in living cells.
通过阻断分子内扭曲的内电荷转移（TICT）过程，我们设计并合成了首个基于TICT的硫化氢荧光探针。该新型探针具有高选择性、良好的膜通透性，适用于活细胞中外源和内源性硫化氢的可视化。
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