Essén B
Ann N Y Acad Sci. 1977;301:30-44. doi: 10.1111/j.1749-6632.1977.tb38183.x.
Large stores of intramuscular substrates are found in the different fiber types of human skeletal muscle, and with prolonged exercise both glycogen and triglyceride stores are utilized. The contribution from intramuscular glycogen stores is greatest at higher work intensities while triglyceride stores are utilized at moderate intensities. In man all fiber types have a similar glycogen content whereas the highest lipid content is found in the more oxidative fibers. The muscle metabolism is well adapted to the supply of substrate as well as to the demand for energy. Among several regulatory mechanisms, changes in citrate concentration seems to be an important factor in the interplay between carbohydrate and lipid metabolism.
在人类骨骼肌的不同纤维类型中发现了大量的肌内底物储存，并且随着长时间运动，糖原和甘油三酯储存都会被利用。在较高工作强度下，肌内糖原储存的贡献最大，而甘油三酯储存在中等强度时被利用。在人类中，所有纤维类型的糖原含量相似，而在氧化能力更强的纤维中发现脂质含量最高。肌肉代谢很好地适应了底物供应以及能量需求。在几种调节机制中，柠檬酸浓度的变化似乎是碳水化合物和脂质代谢相互作用中的一个重要因素。
