饮食与乳腺癌风险
Diet and risk of breast cancer.
作者信息
Kotepui Manas
机构信息
Medical Technology Program, School of Allied Health Sciences and Public Health, Walailak University, Thailand.
出版信息
Contemp Oncol (Pozn). 2016;20(1):13-9. doi: 10.5114/wo.2014.40560. Epub 2016 Mar 16.
Abstract
Diet may play a role in both promoting and inhibiting human breast cancer development. In this review, nutritional risk factors such as consumption of dietary fat, meat, fiber, and alcohol, and intake of phytoestrogen, vitamin D, iron, and folate associated with breast cancer are reviewed. These nutritional factors have a variety of associations with breast cancer risk. Type of fat consumed has different effects on risk of breast cancer: consumption of meat is associated with heterocyclic amine (HCA) exposure; different types of plant fiber have various effects on breast cancer risk; alcohol consumption may increase the risk of breast cancer by producing acetaldehyde and reactive oxygen species (ROS); intake of phytoestrogen may reduce risk of breast cancer through genomic and non-genomic action; vitamin D can reduce the risk of breast cancer by inhibiting the process of cancer invasion and metastasis; intake of dietary iron may lead to oxidative stress, DNA damage, and lipid peroxidation; and lower intake of folate may be linked to a higher risk of breast cancer.
摘要
饮食在促进和抑制人类乳腺癌发展过程中可能都发挥着作用。在本综述中，对与乳腺癌相关的营养风险因素进行了综述，例如膳食脂肪、肉类、纤维和酒精的摄入，以及植物雌激素、维生素D、铁和叶酸的摄取。这些营养因素与乳腺癌风险存在多种关联。所摄入脂肪的类型对乳腺癌风险有不同影响：肉类消费与杂环胺（HCA）暴露有关；不同类型的植物纤维对乳腺癌风险有不同作用；饮酒可能通过产生乙醛和活性氧（ROS）增加乳腺癌风险；植物雌激素的摄入可能通过基因组和非基因组作用降低乳腺癌风险；维生素D可通过抑制癌症侵袭和转移过程降低乳腺癌风险；膳食铁的摄入可能导致氧化应激、DNA损伤和脂质过氧化；而叶酸摄入量较低可能与较高的乳腺癌风险相关。
相似文献
1
Diet and risk of breast cancer.饮食与乳腺癌风险
Contemp Oncol (Pozn). 2016;20(1):13-9. doi: 10.5114/wo.2014.40560. Epub 2016 Mar 16.
2
A prospective study of folate intake and the risk of breast cancer.一项关于叶酸摄入量与乳腺癌风险的前瞻性研究。
JAMA. 1999 May 5;281(17):1632-7. doi: 10.1001/jama.281.17.1632.
3
An epidemiologic approach to studying heterocyclic amines.一种研究杂环胺的流行病学方法。
Mutat Res. 2002 Sep 30;506-507:197-204. doi: 10.1016/s0027-5107(02)00166-5.
4
Dietary intake of meat and meat-derived heterocyclic aromatic amines and their correlation with DNA adducts in female breast tissue.女性乳腺组织中肉类及肉类衍生的杂环芳香胺的膳食摄入量及其与DNA加合物的相关性。
Mutagenesis. 2009 Mar;24(2):127-32. doi: 10.1093/mutage/gen058. Epub 2008 Nov 2.
5
Dietary folate intake and breast cancer risk: results from the Shanghai Breast Cancer Study.膳食叶酸摄入量与乳腺癌风险：上海乳腺癌研究结果
Cancer Res. 2001 Oct 1;61(19):7136-41.
6
Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations.叶酸、甲基相关营养素、酒精以及亚甲基四氢叶酸还原酶（MTHFR）677C→T多态性影响癌症风险：摄入量建议
J Nutr. 2003 Nov;133(11 Suppl 1):3748S-3753S. doi: 10.1093/jn/133.11.3748S.
7
Joint association of fruit, vegetable, and heterocyclic amine intake with DNA damage levels in a general population.水果、蔬菜和杂环胺摄入量与普通人群DNA损伤水平的联合关联。
Nutrition. 2016 Feb;32(2):260-4. doi: 10.1016/j.nut.2015.08.018. Epub 2015 Sep 26.
8
A diet rich in fat and poor in dietary fiber increases the in vitro formation of reactive oxygen species in human feces.
J Nutr. 1997 May;127(5):706-9. doi: 10.1093/jn/127.5.706.
9
Nutrition and primary prevention of breast cancer: foods, nutrients and breast cancer risk.营养与乳腺癌的一级预防：食物、营养素与乳腺癌风险
Eur J Obstet Gynecol Reprod Biol. 2005 Dec 1;123(2):139-49. doi: 10.1016/j.ejogrb.2005.05.011.
10
Red and processed meat, nitrite, and heme iron intakes and postmenopausal breast cancer risk in the NIH-AARP Diet and Health Study.美国国立卫生研究院-美国退休人员协会饮食与健康研究中红肉及加工肉类、亚硝酸盐和血红素铁的摄入量与绝经后乳腺癌风险
Int J Cancer. 2016 Apr 1;138(7):1609-18. doi: 10.1002/ijc.29901. Epub 2015 Nov 20.
引用本文的文献
1
The Role of Nutrition in Low Back Pain: A Narrative Review and Clinical Implications.营养在腰痛中的作用：叙述性综述及临床意义
Am J Lifestyle Med. 2025 Sep 2:15598276251375398. doi: 10.1177/15598276251375398.
2
Mediterranean Diet and Agri-Food By-Products: A Possible Sustainable Approach for Breast Cancer Treatment.地中海饮食与农业食品副产品：一种乳腺癌治疗的可持续可行方法
Antioxidants (Basel). 2025 Jun 26;14(7):789. doi: 10.3390/antiox14070789.
3
Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk.内分泌靶向治疗可改变乳腺微生物群，以降低雌激素受体α型乳腺癌的风险。
Cell Rep Med. 2025 Jan 21;6(1):101880. doi: 10.1016/j.xcrm.2024.101880. Epub 2024 Dec 31.
4
Dietary soluble, insoluble, and total fiber intake and their dietary sources in association with breast cancer.饮食中可溶性、不可溶性和总膳食纤维的摄入量及其食物来源与乳腺癌的关系。
BMC Public Health. 2024 Sep 19;24(1):2560. doi: 10.1186/s12889-024-19861-4.
5
Macronutrient composition of plant-based diets and breast cancer risk: the E3N prospective cohort study.基于植物的饮食的宏量营养素组成与乳腺癌风险：E3N 前瞻性队列研究。
Eur J Nutr. 2024 Aug;63(5):1771-1781. doi: 10.1007/s00394-024-03379-x. Epub 2024 Apr 18.
6
Nutrition Knowledge, Attitudes, and Lifestyle Practices That May Lead to Breast Cancer Risk Reduction among Female University Students in Lebanon.黎巴嫩女大学生中可能降低乳腺癌风险的营养知识、态度和生活方式实践。
Nutrients. 2024 Apr 8;16(7):1095. doi: 10.3390/nu16071095.
7
Healthy Lifestyle and Cancer Risk: Modifiable Risk Factors to Prevent Cancer.健康生活方式与癌症风险：可改变的癌症预防风险因素。
Nutrients. 2024 Mar 11;16(6):800. doi: 10.3390/nu16060800.
8
Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells.咖啡酸苯乙酯（CAPE）协同增强紫杉醇在卵巢癌细胞中的活性。
Molecules. 2023 Aug 1;28(15):5813. doi: 10.3390/molecules28155813.
9
Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.食用/药用蘑菇在乳腺癌中的抗癌潜力。
Int J Mol Sci. 2023 Jun 14;24(12):10120. doi: 10.3390/ijms241210120.
10
Metabolomics Insights into the Differential Response of Breast Cancer Cells to the Phenolic Compounds Hydroxytyrosol and Luteolin.代谢组学揭示了乳腺癌细胞对酚类化合物羟基酪醇和木犀草素的差异反应
Molecules. 2023 May 4;28(9):3886. doi: 10.3390/molecules28093886.
本文引用的文献
1
Intake of specific fruits and vegetables in relation to risk of estrogen receptor-negative breast cancer among postmenopausal women.绝经后妇女摄入特定的水果和蔬菜与雌激素受体阴性乳腺癌风险的关系。
Breast Cancer Res Treat. 2013 Apr;138(3):925-30. doi: 10.1007/s10549-013-2484-3. Epub 2013 Mar 27.
2
Plasma 25-hydroxyvitamin D and the risk of breast cancer in the European prospective investigation into cancer and nutrition: a nested case-control study.血浆 25-羟维生素 D 与欧洲癌症前瞻性调查和营养中的乳腺癌风险：一项巢式病例对照研究。
Int J Cancer. 2013 Oct 1;133(7):1689-700. doi: 10.1002/ijc.28172. Epub 2013 Apr 22.
3
Circulating levels of 25-hydroxyvitamin D and risk of breast cancer: a nested case-control study.25-羟基维生素D的循环水平与乳腺癌风险：一项巢式病例对照研究。
Breast Cancer Res. 2013 Feb 26;15(1):R15. doi: 10.1186/bcr3390.
4
Dietary intake of vitamin D and calcium and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition.膳食维生素 D 和钙的摄入量与欧洲癌症前瞻性调查和营养研究中的乳腺癌风险。
Nutr Cancer. 2013;65(2):178-87. doi: 10.1080/01635581.2013.752018.
5
Dietary intake of folate, B-vitamins and methionine and breast cancer risk among Hispanic and non-Hispanic white women.叶酸、B 族维生素和蛋氨酸的饮食摄入与西班牙裔和非西班牙裔白种妇女的乳腺癌风险。
PLoS One. 2013;8(2):e54495. doi: 10.1371/journal.pone.0054495. Epub 2013 Feb 11.
6
Higher blood 25(OH)D level may reduce the breast cancer risk: evidence from a Chinese population based case-control study and meta-analysis of the observational studies.更高的血液 25(OH)D 水平可能降低乳腺癌风险：基于中国人群的病例对照研究和观察性研究荟萃分析的证据。
PLoS One. 2013;8(1):e49312. doi: 10.1371/journal.pone.0049312. Epub 2013 Jan 30.
7
Isoflavone consumption and risk of breast cancer: a dose-response meta-analysis of observational studies.异黄酮摄入与乳腺癌风险：观察性研究的剂量反应荟萃分析
Asia Pac J Clin Nutr. 2013;22(1):118-27. doi: 10.6133/apjcn.2013.22.1.16.
8
Flavonoids, flavonoid subclasses and breast cancer risk: a meta-analysis of epidemiologic studies.类黄酮、类黄酮亚类与乳腺癌风险：流行病学研究的荟萃分析。
PLoS One. 2013;8(1):e54318. doi: 10.1371/journal.pone.0054318. Epub 2013 Jan 18.
9
Consumption of dairy and meat in relation to breast cancer risk in the Black Women's Health Study.乳制品和肉类消费与黑人女性健康研究中的乳腺癌风险的关系。
Cancer Causes Control. 2013 Apr;24(4):675-84. doi: 10.1007/s10552-013-0146-8. Epub 2013 Jan 18.
10
Alcohol and dietary folate intake and the risk of breast cancer: a case-control study in Japan.饮酒和膳食叶酸摄入与乳腺癌风险：日本的病例对照研究。
Eur J Cancer Prev. 2013 Jul;22(4):358-66. doi: 10.1097/CEJ.0b013e32835b6a60.
Zotero 插件