假性剥脱对角膜透明度的影响。
Effect of Pseudoexfoliation on Corneal Transparency.
作者信息
Cankaya Ali Bulent, Tekin Kemal, Inanc Merve
机构信息
*Department of Ophthalmology, Hacettepe University, Faculty of Medicine, Ankara, Turkey; and †Ophthalmology Clinic, Ulucanlar Eye Research Hospital, Ankara, Turkey.
出版信息
Cornea. 2016 Aug;35(8):1084-8. doi: 10.1097/ICO.0000000000000852.
PURPOSE
To perform a comparison of the corneal optical density (COD) parameters in eyes with pseudoexfoliation syndrome (PES) and age-matched controls.
METHODS
This study was designed as a prospective cross-sectional study. Pentacam HR-Scheimpflug imaging system was used to observe the COD of PES, normal fellow, and normal control eyes. Forty-two patients with unilateral PES and 40 age- and sex-matched normal subjects were included. Group 1 included eyes with PES, group 2 included the clinically unaffected fellow eyes, and group 3 included right eyes of healthy patients. Main outcome measures were densitometry values of the cornea.
RESULTS
There was no significant difference between groups in means of central corneal thickness (P > 0.05). Eyes of unilateral PES patients and eyes of controls differed in COD parameters. Mean total COD in group 1 eyes (21.9 ± 4.9) and group 2 eyes (21.95 ± 5.1) was higher than that in group 3 eyes (17.72 ± 4.7) (P < 0.0001).
CONCLUSIONS
This research demonstrates that the presence of pseudoexfoliation material can cause decrease in the transparency of clear cornea.
目的
比较假性剥脱综合征（PES）患者与年龄匹配的对照者眼睛的角膜光学密度（COD）参数。
方法
本研究设计为前瞻性横断面研究。使用Pentacam HR-Scheimpflug成像系统观察PES患者、对侧正常眼及正常对照眼的COD。纳入42名单侧PES患者和40名年龄及性别匹配的正常受试者。第1组包括PES患者的患眼，第2组包括临床上未受影响的对侧眼，第3组包括健康患者的右眼。主要观察指标为角膜密度测量值。
结果
各组中央角膜厚度均值之间无显著差异（P>0.05）。单侧PES患者的患眼与对照者的眼睛在COD参数方面存在差异。第1组患眼（21.9±4.9）和第2组对侧眼（21.95±5.1）的平均总COD高于第3组眼睛（17.72±4.7）（P<0.0001）。
结论
本研究表明，假性剥脱物质的存在可导致透明角膜透明度降低。
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