改善聚醚醚酮在骨科和牙科应用中生物活性的制备方法：综述
Preparation Methods for Improving PEEK's Bioactivity for Orthopedic and Dental Application: A Review.
作者信息
Almasi Davood, Iqbal Nida, Sadeghi Maliheh, Sudin Izman, Abdul Kadir Mohammed Rafiq, Kamarul Tunku
机构信息
Department of Materials, Manufacturing and Industrial Engineering, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia.
Medical Implant Technology Group (MEDITEG), Faculty of Bioscience and Medical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia.
出版信息
Int J Biomater. 2016;2016:8202653. doi: 10.1155/2016/8202653. Epub 2016 Apr 4.
Abstract
There is an increased interest in the use of polyether ether ketone (PEEK) for orthopedic and dental implant applications due to its elastic modulus close to that of bone, biocompatibility, and its radiolucent properties. However, PEEK is still categorized as bioinert due to its low integration with surrounding tissues. Many studies have reported on methods to increase the bioactivity of PEEK, but there is still one-preparation method for preparing bioactive PEEK implant where the produced implant with desirable mechanical and bioactivity properties is required. The aim of this review is to present the progress of the preparation methods for improvement of the bioactivity of PEEK and to discuss the strengths and weaknesses of the existing methods.
摘要
由于聚醚醚酮（PEEK）的弹性模量接近骨骼、具有生物相容性和射线可透过性，其在骨科和牙科植入应用中的使用受到越来越多的关注。然而，由于PEEK与周围组织的低整合性，它仍被归类为生物惰性材料。许多研究报道了提高PEEK生物活性的方法，但仍需要一种制备具有所需机械和生物活性特性的生物活性PEEK植入物的单一制备方法。本综述的目的是介绍提高PEEK生物活性的制备方法的进展，并讨论现有方法的优缺点。
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