Burns J M, Hogg K J, Hillis W S, Dunn F G
Department of Cardiology, Stobhill General Hospital, Glasgow.
Br Heart J. 1989 Apr;61(4):356-7. doi: 10.1136/hrt.61.4.356.
The case reports of 186 intravenous drug abusers admitted over a three year period were studied. Nineteen had proven staphylococcal septicaemia. Echocardiography showed tricuspid vegetations in seven and aortic vegetations in two. Eighteen out of 19 had systolic murmurs, but only the two patients with aortic vegetations had diastolic murmurs. The chest x ray showed opacities in 10 patients (all those with tricuspid vegetations plus three with normal echocardiograms). Four patients died during follow up, including both those with aortic vegetations; both mitral and tricuspid vegetations were found at necropsy in the other two. All remaining patients were alive at one year. The presence of tricuspid vegetations in intravenous drug abusers is associated with opacities on chest x ray, but carries a good short term prognosis. But these results suggest a poor outcome when left sided endocarditis is present in intravenous drug abusers.
对186名在三年期间收治的静脉注射毒品成瘾者的病例报告进行了研究。其中19人确诊为葡萄球菌败血症。超声心动图显示7人有三尖瓣赘生物，2人有主动脉瓣赘生物。19人中有18人有收缩期杂音，但只有2名有主动脉瓣赘生物的患者有舒张期杂音。胸部X光显示10名患者有肺部浸润（所有有三尖瓣赘生物的患者加上3名超声心动图正常的患者）。4名患者在随访期间死亡，包括2名有主动脉瓣赘生物的患者；另外2名患者尸检时发现有二尖瓣和三尖瓣赘生物。所有其余患者一年时仍存活。静脉注射毒品成瘾者中三尖瓣赘生物的存在与胸部X光肺部浸润有关，但短期预后良好。但这些结果表明，静脉注射毒品成瘾者出现左侧心内膜炎时预后较差。
