Zouzias Ioannis C, Bugbee William D
*Kerlan-Jobe Orthopaedic Clinic, Los Angeles †Division of Orthopaedic Surgery, Scripps Clinic ‡Department of Bioengineering, University of California-San Diego, La Jolla, CA.
Sports Med Arthrosc Rev. 2016 Jun;24(2):79-84. doi: 10.1097/JSA.0000000000000109.
The technique of osteochondral allograft (OCA) transplantation has been used to treat a wide spectrum of cartilage deficiencies in the knee. Its use has been supported by basic science and clinical studies that show it is a safe and effective treatment option. What sets fresh OCA transplantation apart from other cartilage procedures in the knee, is the ability to treat large defects with mature hyaline cartilage. Studies looking at transplantation of fresh OCAs in the general population have shown reliable pain relief and return to activities of daily living. Reports of cartilage injuries in athletes have risen over the years and more research is needed in evaluating the successfulness of OCA transplantation in the athletic population.
同种异体骨软骨移植（OCA）技术已被用于治疗膝关节广泛的软骨缺损。基础科学和临床研究支持其应用，表明它是一种安全有效的治疗选择。新鲜OCA移植与膝关节其他软骨手术的不同之处在于，它有能力用成熟的透明软骨治疗大面积缺损。对普通人群新鲜OCA移植的研究表明，能可靠地缓解疼痛并恢复日常生活活动。多年来，运动员软骨损伤的报告有所增加，在评估OCA移植在运动员群体中的成功率方面还需要更多研究。
