Filatov M A, Khramova Y V, Kiseleva M V, Malinova I V, Komarova E V, Semenova M L
Faculty of Biology,Lomonosov Moscow State University,Leninskie Gory 1,bld. 12,Moscow 119991,Russia.
Medical Radiological Research Centre,Ministry of Health of the Russian Federation (MMRC),Koroleva st. 4,Obninsk 249036,Russia.
Zygote. 2016 Oct;24(5):635-53. doi: 10.1017/S096719941600006X. Epub 2016 May 4.
In the present review, the main strategies of female fertility preservation are covered. Procedures of fertility preservation are necessary for women who suffer from diseases whose treatment requires the use of aggressive therapies, such as chemotherapy and radiotherapy. These kinds of therapy negatively influence the health of gametes and their progenitors. The most commonly used method of female fertility preservation is ovarian tissue cryopreservation, followed by the retransplantation of thawed tissue. Another approach to female fertility preservation that has been actively developed lately is the ovarian tissue in vitro culture. The principal methods, advantages and drawbacks of these two strategies are discussed in this article.
在本综述中，涵盖了女性生育力保存的主要策略。对于患有需要使用化疗和放疗等积极治疗手段的疾病的女性来说，生育力保存程序是必要的。这类治疗会对配子及其祖细胞的健康产生负面影响。女性生育力保存最常用的方法是卵巢组织冷冻保存，随后进行解冻组织的再移植。最近积极发展的另一种女性生育力保存方法是卵巢组织体外培养。本文讨论了这两种策略的主要方法、优点和缺点。
