Révész L, Siracka E, Siracky J, Delides G, Pavlaki K
Department of Tumor Biology II, Karolinska Institute, Stockholm, Sweden.
Int J Radiat Oncol Biol Phys. 1989 May;16(5):1161-3. doi: 10.1016/0360-3016(89)90274-5.
Vascular density in different regions of a number of uterine cervix carcinomas was determined by morphometric analysis of stained histologic sections. Variance analysis indicated a larger inter- than intra-tumoral inhomogeneity of the vasculature, suggesting a certain individual vascularization pattern in these tumors. As indicated by a retrospective study of archival biopsies, this pattern has a predictive value in regard to the efficacy of radiotherapy.
通过对染色组织切片进行形态计量分析，确定了多个子宫颈癌不同区域的血管密度。方差分析表明，肿瘤内血管的异质性大于肿瘤间的异质性，提示这些肿瘤存在一定的个体血管生成模式。一项对存档活检的回顾性研究表明，这种模式对放疗疗效具有预测价值。
