Chan Philemon, Ho Kevin, Ryan Allen F
L-3 Applied Technologies, Inc., 10770 Wateridge Circle, Suite 200, San Diego, CA 92121-5701.
UCSD School of Medicine and San Diego VA Medical Center, 9500 Gilman Drive, La Jolla, CA 92093.
Mil Med. 2016 May;181(5 Suppl):59-69. doi: 10.7205/MILMED-D-15-00139.
The new Auditory 4.0 model has been developed for the assessment of auditory outcomes, expressed as temporary threshold shift (TTS) and permanent threshold shift (PTS), from exposures to impulse noise for unprotected ears, including the prediction of TTS recovery.
Auditory 4.0 is an empirical model, constructed from test data collected from chinchillas exposed to impulse noise in the laboratory. Injury outcomes are defined as TTS and PTS, and Auditory 4.0 provides the full range of TTS and PTS dose-response curves with the risk factor constructed from A-weighted sound exposure level. Human data from large weapons noise exposure was also used to guide the development of the recovery model.
Guided by data, a 28-dBA shift was applied to the dose-response curves to account for the scaling from chinchillas to humans. Historical data from rifle noise tests were used to validate the dose-response curves. New chinchilla tests were performed to collect recovery data to construct the TTS recovery model.
Auditory 4.0 is the only model known to date that provides the full TTS and PTS dose-response curves, including a TTS recovery model. The model shows good agreement with historical data.
已开发出新的听觉4.0模型，用于评估未受保护耳朵暴露于脉冲噪声后的听觉结果，以暂时阈移（TTS）和永久阈移（PTS）表示，包括预测TTS恢复情况。
听觉4.0是一个经验模型，由在实验室中暴露于脉冲噪声的龙猫收集的测试数据构建而成。损伤结果定义为TTS和PTS，听觉4.0提供了完整的TTS和PTS剂量反应曲线，其风险因子由A加权声暴露级构建。来自大型武器噪声暴露的人类数据也用于指导恢复模型的开发。
以数据为指导，对剂量反应曲线应用28分贝的偏移，以考虑从龙猫到人类的尺度变化。步枪噪声测试的历史数据用于验证剂量反应曲线。进行了新的龙猫测试以收集恢复数据，构建TTS恢复模型。
听觉4.0是迄今为止已知的唯一提供完整TTS和PTS剂量反应曲线（包括TTS恢复模型）的模型。该模型与历史数据显示出良好的一致性。
