Kim Ju Young, You Yong Sung, Kim Soon Hyun, Kwon Oh Woong
Retina Center, Nune Eye Hospital, Seoul, Korea.
Retin Cases Brief Rep. 2017;11(3):227-231. doi: 10.1097/ICB.0000000000000327.
A retrospective case report of a retinitis pigmentosa patient who underwent vitrectomy for epiretinal membrane after intravitreal autologous stem cell implantation.
A 71-year-old female RP patient came to our clinic for ophthalmic evaluation after intravitreal autologous stem cell injection. Four months ago, she underwent intravitreal autologous stem cell injection for both eyes at another hospital. New thick epiretinal membrane (ERM) with extensive macular pucker was found on her left eye. She underwent pars plana vitrectomy and membranectomy. After biopsy, many CD34-positive stem cells were detected in ERM specimen.
This is the first report of ERM formation following intravitreal autologous stem cells injection. CD34-positive stem cells were detected in a human eye at 4 months after injection. Further studies are needed to determine how stem cells caused ERM and how long they would stay in the eye.
一份关于一名视网膜色素变性患者的回顾性病例报告，该患者在玻璃体内自体干细胞植入后因视网膜前膜接受了玻璃体切除术。
一名71岁的女性视网膜色素变性患者在玻璃体内自体干细胞注射后来到我们诊所进行眼科评估。四个月前，她在另一家医院接受了双眼玻璃体内自体干细胞注射。在她的左眼发现了新的增厚的视网膜前膜（ERM）并伴有广泛的黄斑皱襞。她接受了玻璃体切除术和平坦部膜切除术。活检后，在视网膜前膜标本中检测到许多CD34阳性干细胞。
这是关于玻璃体内自体干细胞注射后形成视网膜前膜的首例报告。注射后4个月在人眼中检测到CD34阳性干细胞。需要进一步研究以确定干细胞如何导致视网膜前膜形成以及它们会在眼中停留多长时间。
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