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腹腔镜袖状胃切除术治疗病态肥胖症的长期结果:5至8年的结果

Long-Term Results of Laparoscopic Sleeve Gastrectomy for Morbid Obesity: 5 to 8-Year Results.

作者信息

Gadiot Ralph P M, Biter L Ulas, van Mil Stefanie, Zengerink Hans F, Apers J, Mannaerts Guido H H

机构信息

Sint Fransiscus Gasthuis, Rotterdam, Netherlands.

出版信息

Obes Surg. 2017 Jan;27(1):59-63. doi: 10.1007/s11695-016-2235-8.

DOI:10.1007/s11695-016-2235-8
PMID:27178407
Abstract

INTRODUCTION

Although long-term results of sleeve gastrectomy (LSG) remain scarce in the literature, its popularity as a stand-alone procedure has accounted for a global increase in LSG performance. In this retrospective study, the authors present 5 to 8-year follow-up results in terms of weight loss, failure/revision rate, and comorbidity resolution from a single center.

MATERIALS AND METHODS

A prospectively maintained database was reviewed for patients who underwent LSG between 2007 and 2010. Data analysis on weight loss, comorbid conditions, revision surgery, and mortality was conducted.

RESULTS

Median percentage excess BMI loss (%EBMIL) was 59.0, and 53.9 %, and median percentage total weight loss (%TWL) was 25.1, and 22.9 % at 5 and 8 years, respectively. Revision to gastric bypass due to insufficient weight loss or gastroesophageal reflux disease (GERD) was performed in 42 patients (15.2 %). Resolution of comorbid condition was achieved in 91 % of patients with obstructive sleep apnea syndrome (OSAS), 68 % of patients with type 2 diabetes (T2DM), 53 % of patients with hypertension, and 25 % of patients with dyslipedemia. Loss to follow-up rate was 45 % at 5 years, 28 % at 6 years, 23 % at 7 years, and 13 % at 8 years.

CONCLUSION

This study adds to the currently available data confirming the LSG to be a safe and effective procedure at long term. Data from high-volume studies are needed to establish the definite role of the LSG in the spectrum of bariatric procedures.

摘要

引言

尽管袖状胃切除术(LSG)的长期结果在文献中仍然较少,但它作为一种独立手术的普及导致了全球范围内LSG手术量的增加。在这项回顾性研究中,作者呈现了来自单一中心的5至8年随访结果,涉及体重减轻、失败/翻修率以及合并症缓解情况。

材料与方法

对一个前瞻性维护的数据库进行回顾,纳入2007年至2010年间接受LSG的患者。对体重减轻、合并症情况、翻修手术和死亡率进行数据分析。

结果

5年和8年时,平均超重BMI损失百分比(%EBMIL)分别为59.0%和53.9%,平均总体重减轻百分比(%TWL)分别为25.1%和22.9%。42例患者(15.2%)因体重减轻不足或胃食管反流病(GERD)而翻修为胃旁路手术。91%的阻塞性睡眠呼吸暂停综合征(OSAS)患者、68%的2型糖尿病(T2DM)患者、53%的高血压患者和25%的血脂异常患者的合并症得到缓解。5年、6年、7年和8年的失访率分别为45%、28%、23%和13%。

结论

本研究补充了现有数据,证实LSG长期而言是一种安全有效的手术。需要来自大量研究的数据来确定LSG在减肥手术领域中的明确作用。

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