Hakim Wasim, Kamanahalli Raghavendra, Dick Elizabeth, Bharwani Nishat, Fetherston Shirley, Kashef Elika
1 Department of Radiology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
2 Royal Lancaster Infirmary, UHMB NHS Trust, Lancaster, UK.
Br J Radiol. 2016 Jul;89(1063):20160160. doi: 10.1259/bjr.20160160. Epub 2016 May 17.
To compare the image quality of conventional arterial and portal venous (PV) phase multidetector CT (MDCT) with two biphasic injection protocols in polytrauma patients.
60 consecutive patients with polytrauma underwent body 256-slice MDCT with a conventional protocol or 1 of 2 single-pass biphasic protocols: Group A, arterial (30 s) and PV (60 s) phase acquisitions; Group B, "biphasic" contrast injection with a single acquisition at 60 s; and Group C, "modified biphasic" injection with a single acquisition at a 70-s delay. Images were analyzed for arterial, venous and parenchymal attenuation profiles with regions of interest in the major arteries, veins and solid abdominal organs. A 5-point scoring system was used to assess the image quality, with 5 representing excellent arterial, venous and parenchymal opacification and <3 representing non-diagnostic opacification. In addition, the effective dose (millisieverts) was compared between the groups.
In 93% of patients, image quality was scored as good or excellent (≥4). All studies were of satisfactory diagnostic quality. Overall, venous and arterial attenuation profiles were comparable. Attenuation profiles in the solid abdominal viscera were significantly higher (p < 0.01) using both biphasic protocols than with arterial or PV phase of conventional protocols. Effective doses were higher in Group A.
Comparable image quality can be achieved using a biphasic i.v. contrast injection protocol with single MDCT acquisition with less radiation and reduction in acquisition time.
For these particular biphasic injection protocols, we have shown that image quality is comparable with a conventional protocol. This has been achieved by comparing enhanced densities of specific structures, as well as gestalt scoring by assessors, on a 256-slice MDCT.
比较在多发伤患者中,采用两种双期注射方案的传统动脉期和门静脉期多层螺旋CT(MDCT)的图像质量。
60例连续的多发伤患者接受了256层MDCT全身扫描,采用传统方案或两种单期双期方案中的一种:A组,动脉期(30秒)和门静脉期(60秒)采集;B组,“双期”对比剂注射,在60秒时单次采集;C组,“改良双期”注射,在延迟70秒时单次采集。在主要动脉、静脉和腹部实性器官中设置感兴趣区,分析图像的动脉、静脉和实质期衰减曲线。采用5分评分系统评估图像质量,5分表示动脉、静脉和实质期强化极佳,<3分表示强化不能用于诊断。此外,比较各组的有效剂量(毫西弗)。
93%的患者图像质量评分为良好或极佳(≥4分)。所有研究的诊断质量均令人满意。总体而言,静脉和动脉期衰减曲线具有可比性。与传统方案的动脉期或门静脉期相比,两种双期方案在腹部实性脏器中的衰减曲线均显著更高(p<0.01)。A组的有效剂量更高。
采用双期静脉注射对比剂方案并单次MDCT采集,可获得相当的图像质量,同时减少辐射并缩短采集时间。
对于这些特定的双期注射方案,我们已表明图像质量与传统方案相当。这是通过在256层MDCT上比较特定结构的强化密度以及评估者的整体评分来实现的。