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地中海饮食与与年龄相关的认知功能:研究结果和神经心理学评估方法的系统评价。

The Mediterranean diet and age-related cognitive functioning: A systematic review of study findings and neuropsychological assessment methodology.

机构信息

a School of Psychology, Social Work and Social Policy , University of South Australia , Adelaide , Australia.

b Nutritional Physiology Research Centre (NPRC) , Adelaide , Australia.

出版信息

Nutr Neurosci. 2017 Oct;20(8):449-468. doi: 10.1080/1028415X.2016.1183341. Epub 2016 May 18.

DOI:10.1080/1028415X.2016.1183341
PMID:27192034
Abstract

OBJECTIVES

The primary aims of this review were to identify studies investigating the association between the MedDiet pattern and age-related cognitive function, to determine the current status of knowledge, and to ascertain whether a lack of standardization with the operationalization of age-related cognitive function and differences in the chosen neuropsychological assessment methodology impacted on the results and findings.

METHODS

The systematic review protocol for this paper was carried out following the statement and general principles of PRISMA and the UK Centre for Reviews and Dissemination (CRD).

RESULTS

A systematic search of electronic databases yielded two cross-sectional studies, two cross-sectional/prospective studies, and 11 prospective studies for inclusion. Among this group of studies, conflicting results and conclusions regarding the efficacy of the MedDiet as a therapeutic approach for age-related cognitive function were found. Of importance, clear differences among studies in relation to neuropsychological assessment methodology were identified. Such disparity appeared to be one plausible factor contributing to the lack of consensus among study findings.

DISCUSSION

One of the important challenges for future research will be to aim toward some kind of standardized neuropsychological assessment criteria. This type of endeavor will enable the ability to validate with greater confidence, whether or not adherence to a MedDiet does promote benefit for age-related cognitive function.

摘要

目的

本综述的主要目的是确定研究地中海饮食模式与年龄相关认知功能之间关联的研究,以确定当前的知识状况,并确定年龄相关认知功能的操作和选择的神经心理学评估方法的差异是否缺乏标准化,从而影响结果和发现。

方法

本文的系统评价方案遵循 PRISMA 声明和英国评论传播中心(CRD)的原则和指南。

结果

系统搜索电子数据库得到了两项横断面研究、两项横断面/前瞻性研究和 11 项前瞻性研究。在这组研究中,发现了关于地中海饮食作为治疗与年龄相关认知功能的方法的功效的相互矛盾的结果和结论。重要的是,还确定了研究中神经心理学评估方法存在明显差异。这种差异似乎是导致研究结果缺乏共识的一个合理因素。

讨论

未来研究的一个重要挑战将是旨在制定某种标准化的神经心理学评估标准。这种努力将能够更有信心地验证,遵守地中海饮食是否确实有助于年龄相关的认知功能。

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