Norsted T L, White E
Fred Hutchinson Cancer Research Center, Seattle, Washington 98104.
Int J Epidemiol. 1989 Mar;18(1):22-7. doi: 10.1093/ije/18.1.22.
The incidence of cancer among Native Americans in Alaska, Canada, and the south western United States has been reportedly low relative to the Caucasian populations in these areas. We investigated the incidence of cancer among the Native Americans of Western Washington for the time period 1974-1983 and compared it to that of the Caucasian population using two types of analyses, age-standardized incidence ratios (SIR) and proportional cancer incidence ratios (PIR). Native Americans of this area were found to be at lower risk of cancer than Caucasians at almost all ages. The age-standardized incidence ratio (SIR) for all cancer sites was 0.4 (p less than 0.01) for males and 0.6 (p less than 0.01) for females. A relative excess of cancer of the cervix (SIR = 1.6, PIR = 2.1, p less than 0.05) was found among Native American females. Significant deficits were found for corpus uterine cancer among females (SIR = 0.2, PIR = 0.5, p less than 0.05) and cancer of the prostate among males (SIR = 0.2, PIR = 0.5, p less than 0.05). A suggestive increase in the risk of cancer of the gallbladder was discovered for males and females. This is the first report on cancer incidence among Native Americans in Western Washington.
据报道，阿拉斯加、加拿大和美国西南部的美洲原住民患癌率相对于这些地区的白种人较低。我们调查了1974年至1983年期间华盛顿州西部美洲原住民的癌症发病率，并通过年龄标准化发病率比（SIR）和癌症比例发病率（PIR）这两种分析方法，将其与白种人的发病率进行了比较。结果发现，该地区的美洲原住民在几乎所有年龄段患癌风险都低于白种人。所有癌症部位的年龄标准化发病率比（SIR），男性为0.4（p<0.01），女性为0.6（p<0.01）。美洲原住民女性中子宫颈癌相对高发（SIR = 1.6，PIR = 2.1，p<0.05）。女性子宫体癌（SIR = 0.2，PIR = 0.5，p<0.05）和男性前列腺癌（SIR = 0.2，PIR = 0.5，p<0.05）显著低发。发现男性和女性患胆囊癌的风险有增加迹象。这是关于华盛顿州西部美洲原住民癌症发病率的首份报告。
