Health Research Institute, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan.
Biomedical Research Institute, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan.
Adv Healthc Mater. 2016 May;5(10):1246. doi: 10.1002/adhm.201670051.
A plain mesoporous silica (MS) nanoparticle without any immunomodulatory molecules enhances anti-cancer immunity in vivo. On page 1169, X.P. Wang, N. M. Tsuji, A. Ito and co-workers show that a plain MS nanoparticle promotes both Th1 and Th2 immune responses, and enhances the effector memory of CD4(+) and CD8(+) T cell populations in the three most important immune organs (bone marrow, lymph node and spleen) of mice.
一种没有任何免疫调节分子的普通介孔硅纳米颗粒在体内增强了抗癌免疫。在第 1169 页，X.P. Wang、N.M. Tsuji、A. Ito 及其同事表明，普通 MS 纳米颗粒促进了 Th1 和 Th2 免疫反应，并增强了小鼠三个最重要的免疫器官（骨髓、淋巴结和脾脏）中 CD4(+)和 CD8(+)T 细胞群体的效应记忆。
