Heitsch H, König W A, Decker H, Bormann C, Fiedler H P, Zähner H
Institute of Organic Chemistry, University of Hamburg, FRG.
J Antibiot (Tokyo). 1989 May;42(5):711-7. doi: 10.7164/antibiotics.42.711.
Two new nikkomycins were isolated from the fermentation broth of Streptomyces tendae Tü 901/PF 53+-3. These new metabolites, nikkomycins pseudo-Z (psi-Z,1) and pseudo-J (psi-J, 2) differ from the corresponding nikkomycins Z and J by a C-glycosidic bond between C-5 of uracil and C-1' of 5-amino-5-deoxy-D-allo-furanuronic acid instead of an N-glycosidic bond. The structure elucidation was achieved by two-dimensional NMR techniques and mass spectrometry.
从天蓝色链霉菌Tü 901/PF 53+-3的发酵液中分离出两种新的多氧霉素。这些新的代谢产物，多氧霉素假Z（psi-Z，1）和假J（psi-J，2），与相应的多氧霉素Z和J的区别在于，尿嘧啶的C-5与5-氨基-5-脱氧-D-阿洛呋喃糖醛酸的C-1'之间是C-糖苷键，而不是N-糖苷键。通过二维核磁共振技术和质谱对其结构进行了鉴定。
