Armstrong James Pk, Perriman Adam W
School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK Centre for Organized Matter Chemistry and Centre for Protolife Research, School of Chemistry, University of Bristol, Bristol BS8 1TS, UK
Exp Biol Med (Maywood). 2016 May;241(10):1098-106. doi: 10.1177/1535370216650291.
The ability to rationally manipulate and augment the cytoplasmic membrane can be used to overcome many of the challenges faced by conventional cellular therapies and provide innovative opportunities when combined with new biotechnologies. The focus of this review is on emerging strategies used in cell functionalization, highlighting both pioneering approaches and recent developments. These will be discussed within the context of future directions in this rapidly evolving field.
合理操纵和增强细胞质膜的能力可用于克服传统细胞疗法面临的许多挑战,并与新生物技术结合时提供创新机会。本综述的重点是细胞功能化中使用的新兴策略,突出了开创性方法和最新进展。这些将在这个快速发展领域的未来方向背景下进行讨论。