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人类胎儿、新生儿及儿童代谢和内分泌应激反应的个体发生。

The ontogeny of the metabolic and endocrine stress response in the human fetus, neonate and child.

作者信息

Platt M P, Anand K J, Aynsley-Green A

机构信息

Department of Child Health, University of Newcastle upon Tyne, Medical School, UK.

出版信息

Intensive Care Med. 1989;15 Suppl 1:S44-5. doi: 10.1007/BF00260885.

DOI:10.1007/BF00260885
PMID:2723248
Abstract

Evidence of an endocrine and metabolic response to stress is evident from the mid trimester of fetal life. The ontogeny of this response is seen in the different patterns of response evident in the fetus, neonate, infant and child. These data raise important issues concerning the management of pain and stress in early life.

摘要

从胎儿期中期开始,就有证据表明存在对压力的内分泌和代谢反应。这种反应的个体发生可见于胎儿、新生儿、婴儿和儿童明显不同的反应模式中。这些数据提出了关于早期生活中疼痛和压力管理的重要问题。

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本文引用的文献

1
Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response.芬太尼麻醉在早产儿手术中的随机试验:对应激反应的影响。
Lancet. 1987 Jan 31;1(8527):243-8. doi: 10.1016/s0140-6736(87)90065-1.
2
Preterm infants are more prone to complications following minor surgery than are term infants.与足月儿相比,早产儿在接受小手术后更容易出现并发症。
Anesthesiology. 1982 Apr;56(4):304-6. doi: 10.1097/00000542-198204000-00013.
3
Can the human neonate mount an endocrine and metabolic response to surgery?
J Pediatr Surg. 1985 Feb;20(1):41-8. doi: 10.1016/s0022-3468(85)80390-0.
4
The metabolic and endocrine milieu of the human fetus at 18-21 weeks of gestation. II. Blood glucose, lactate, pyruvate and ketone body concentrations.妊娠18 - 21周时人类胎儿的代谢和内分泌环境。II. 血糖、乳酸、丙酮酸和酮体浓度。
Biol Neonate. 1985;47(1):19-25. doi: 10.1159/000242086.
5
Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses.生长受限胎儿的产前窒息、高乳酸血症、低血糖症和胎儿成红细胞增多症。
Br Med J (Clin Res Ed). 1987 Apr 25;294(6579):1051-3. doi: 10.1136/bmj.294.6579.1051.
6
Analgesia and anaesthesia in newborn babies and infants.新生儿和婴儿的镇痛与麻醉
Lancet. 1987 May 9;1(8541):1090.
7
Ligation of patent ductus arteriosus in premature infants.早产儿动脉导管未闭的结扎术。
Br J Anaesth. 1976 Apr;48(4):365-9. doi: 10.1093/bja/48.4.365.
8
Second annual Jonathan E. Rhoads Lecture. The metabolic response to injury and its nutritional implications: retrospect and prospect.第二届乔纳森·E·罗兹年度讲座。损伤的代谢反应及其营养意义:回顾与展望。
JPEN J Parenter Enteral Nutr. 1979 May-Jun;3(3):108-29. doi: 10.1177/014860717900300302.
9
Gut hormones in fetal distress.
Lancet. 1979 Nov 3;2(8149):968. doi: 10.1016/s0140-6736(79)92670-9.
10
Fetal distress, meconium, and motilin.
Lancet. 1979 Mar 31;1(8118):718. doi: 10.1016/s0140-6736(79)91163-2.