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妊娠18 - 21周时人类胎儿的代谢和内分泌环境。II. 血糖、乳酸、丙酮酸和酮体浓度。

The metabolic and endocrine milieu of the human fetus at 18-21 weeks of gestation. II. Blood glucose, lactate, pyruvate and ketone body concentrations.

作者信息

Aynsley-Green A, Soltesz G, Jenkins P A, Mackenzie I Z

出版信息

Biol Neonate. 1985;47(1):19-25. doi: 10.1159/000242086.

DOI:10.1159/000242086
PMID:3967054
Abstract

Blood levels of glucose, lactate, pyruvate and total ketone bodies were measured in 16 conscious mothers and their minimally stressed fetuses at 18-21 weeks gestation. Blood samples were taken from the maternal antecubital vein and from the fetal umbilical vein and artery during fetoscopy prior to termination of pregnancy. The mean concentrations of blood glucose, lactate and pyruvate were similar in maternal and fetal venous blood; no significant difference was found between the fetal umbilical artery and vein concentrations. Maternal total blood ketone body levels were significantly higher than fetal levels with no detectable umbilical venous arterial concentration difference. There was a significant inverse relationship between the umbilical artery levels and the umbilical venous-arterial concentration differences for blood glucose and lactate.

摘要

在妊娠18 - 21周时,对16名清醒的母亲及其应激最小的胎儿的血糖、乳酸、丙酮酸和总酮体水平进行了测量。在终止妊娠前进行胎儿镜检查时,从母亲的肘前静脉以及胎儿的脐静脉和动脉采集血样。母亲和胎儿静脉血中的血糖、乳酸和丙酮酸平均浓度相似;胎儿脐动脉和静脉浓度之间未发现显著差异。母亲的全血总酮体水平显著高于胎儿水平,脐静脉和动脉浓度之间未检测到差异。脐动脉水平与血糖和乳酸的脐静脉 - 动脉浓度差异之间存在显著的负相关关系。

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