Jitprapaikulsan Jiraporn, Siritho Sasitorn, Prayoonwiwat Naraporn
Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand; Bumrungrad International Hospital, Sukhumvit 3, Bangkok 10110, Thailand.
J Neuroimmunol. 2016 Jun 15;295-296:75-8. doi: 10.1016/j.jneuroim.2016.03.016. Epub 2016 Apr 14.
Vitamin D status of Thai clinically isolated syndrome (CIS), multiple sclerosis (MS) and NMO/neuromyelitis optica spectrum disorders (NMOSD) patients were prospectively collected (N=130). Its associations with disability score, and disease activity were sought. Mean vitamin D levels were not significantly different (CIS, 22.18±8.2; MS, 23.41±11.9; NMO/NMOSD, 23.54±9.3ng/mL; p=0.857). Prevalence of vitamin D insufficiency and deficiency (≤30ng/mL) was 73-80%. Neither disability score nor disease activity was associated with vitamin D level. Vitamin D insufficiency was common in Thai CIS, MS, and NMO/NMOSD patients without association with disability or disease activity.
前瞻性收集了泰国临床孤立综合征（CIS）、多发性硬化症（MS）和视神经脊髓炎/视神经脊髓炎谱系障碍（NMOSD）患者的维生素D状态（N = 130）。研究了其与残疾评分和疾病活动的关联。维生素D平均水平无显著差异（CIS，22.18±8.2；MS，23.41±11.9；NMO/NMOSD，23.54±9.3ng/mL；p = 0.857）。维生素D不足和缺乏（≤30ng/mL）的患病率为73 - 80%。残疾评分和疾病活动均与维生素D水平无关。维生素D不足在泰国CIS、MS和NMO/NMOSD患者中很常见，与残疾或疾病活动无关。
