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儿童急性腹泻的临床病理研究

Clinicopathogenic studies of acute diarrhea in children.

作者信息

Cai L M, Zhang C, Chen H, Jiang W P, Mao W X

机构信息

Li-Min Cai, Chang Zhang, He Chen, Wei-Ping Jiang, Wen-Xiang Mao, Department of Infectious Diseases, The First People's Municipal Hospital of Wenling, Wenling 317500, Zhejiang Province, China.

出版信息

World J Gastroenterol. 1997 Sep 15;3(3):162. doi: 10.3748/wjg.v3.i3.162.

DOI:10.3748/wjg.v3.i3.162
PMID:27239134
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4842875/
Abstract

AIM

To identify etiologic pathogens of acute diarrhea in children and to determine the diagnostic value of stool pH.

METHODS

From May 1988 to April 1992, 368 children with acute diarrhea were studied. Fresh stools were routinely examined, and stool pH was tested with pH paper. Samples were placed in Cary-Blair culture medium and were sent to the lab for bacterial isolation and identification. Rotavirus was identified in the supernatant by ELISA.

RESULTS

Thirty-one pathogens and 385 bacterial strains were found in the 368 samples, with a detection rate of 67.7%, including 37.8% of mixed infections. Among the bacteria families, vibrionaceae was the most common (39.7%), and among bacteria genera, aeromonas was the most common (26.8%). In bacterial diarrhea, stool pH tended to be basic, while in viral diarrhea it tended to be acidic.

CONCLUSION

There are 31 pathogens for children's acute diarrhea in this area. It is quite difficult to make an etiologic diagnosis only by clinical signs. However, stool pH is of some value for early disease diagnosis.

摘要

目的

确定儿童急性腹泻的病原体,并评估粪便pH值的诊断价值。

方法

1988年5月至1992年4月,对368例急性腹泻儿童进行研究。常规检查新鲜粪便,并用pH试纸检测粪便pH值。样本置于Cary-Blair培养基中,送至实验室进行细菌分离和鉴定。通过ELISA法在上清液中鉴定轮状病毒。

结果

368份样本中发现31种病原体和385株细菌,检出率为67.7%,其中混合感染率为37.8%。在细菌科中,弧菌科最为常见(39.7%),在细菌属中,气单胞菌最为常见(26.8%)。细菌性腹泻时,粪便pH值倾向于碱性,而病毒性腹泻时则倾向于酸性。

结论

该地区儿童急性腹泻有31种病原体。仅通过临床症状进行病因诊断相当困难。然而,粪便pH值对疾病早期诊断有一定价值。

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