• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
The Role of Blue Dye in Sentinel Node Detection for Breast Cancer: A Retrospective Study of 203 Patients.蓝色染料在乳腺癌前哨淋巴结检测中的作用：对203例患者的回顾性研究
Breast Care (Basel). 2016 Apr;11(2):128-32. doi: 10.1159/000445368. Epub 2016 Apr 26.
2
Role of routine preoperative lymphoscintigraphy in sentinel node biopsy for breast cancer.常规术前淋巴闪烁显像在乳腺癌前哨淋巴结活检中的作用。
Eur J Cancer. 2005 Jan;41(2):238-43. doi: 10.1016/j.ejca.2004.05.008.
3
Comparison of blue dye and isotope with blue dye alone in breast sentinel node biopsy.乳腺前哨淋巴结活检中蓝色染料与同位素联合使用及单独使用蓝色染料的比较。
ANZ J Surg. 2005 Sep;75(9):817-21. doi: 10.1111/j.1445-2197.2005.03531.x.
4
Blue dye versus combined blue dye-radioactive tracer technique in detection of sentinel lymph node in breast cancer.蓝色染料与蓝色染料-放射性示踪剂联合技术在乳腺癌前哨淋巴结检测中的应用比较
Eur J Surg Oncol. 2004 Nov;30(9):913-7. doi: 10.1016/j.ejso.2004.08.003.
5
A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.一种混合放射性和荧光示踪剂用于阴茎癌前哨淋巴结活检，有望替代蓝色染料。
Eur Urol. 2014 Mar;65(3):600-9. doi: 10.1016/j.eururo.2013.11.014. Epub 2013 Nov 26.
6
[Sentinel node biopsy for breast cancer patients at the Bács-Kiskun County Teaching Hospital].[巴奇-基什孔县教学医院乳腺癌患者的前哨淋巴结活检]
Orv Hetil. 2002 Mar 3;143(9):437-46.
7
Observational study of blue dye-assisted four-node sampling for axillary staging in early breast cancer.观察性研究：蓝染料辅助早期乳腺癌腋窝分期的四节点取样
Eur J Surg Oncol. 2010 Aug;36(8):731-6. doi: 10.1016/j.ejso.2010.06.011. Epub 2010 Jul 7.
8
Sentinel lymph node as a new marker for therapeutic planning in breast cancer patients.前哨淋巴结作为乳腺癌患者治疗规划的新标志物。
J Surg Oncol. 2004 Mar;85(3):102-11. doi: 10.1002/jso.20022.
9
Determinants for non-sentinel node metastases in primary invasive breast cancer: a population-based cohort study of 602 consecutive patients with sentinel node metastases.原发性浸润性乳腺癌中前哨淋巴结以外转移的决定因素：602 例前哨淋巴结转移连续患者的基于人群队列研究。
BMC Cancer. 2019 Jun 25;19(1):626. doi: 10.1186/s12885-019-5823-x.
10
Sentinel lymph node mapping in early-stage breast cancer: technical issues and results with vital blue dye mapping and radioguided surgery.早期乳腺癌前哨淋巴结定位：活性蓝色染料定位及放射性导向手术的技术问题与结果
J Surg Oncol. 2000 May;74(1):61-8. doi: 10.1002/1096-9098(200005)74:1<61::aid-jso14>3.0.co;2-9.

本文引用的文献

1
The Value of Isosulfan Blue Dye in Addition to Isotope Scanning in the Identification of the Sentinel Lymph Node in Breast Cancer Patients With a Positive Lymphoscintigraphy: A Randomized Controlled Trial (ISRCTN98849733).异硫蓝染料联合同位素扫描在淋巴闪烁显像阳性的乳腺癌患者前哨淋巴结识别中的价值：一项随机对照试验（ISRCTN98849733）
Ann Surg. 2015 Aug;262(2):243-8. doi: 10.1097/SLA.0000000000001213.
2
Processing sentinel nodes in breast cancer: when and how many?乳腺癌前哨淋巴结的处理：时机与数量？
Arch Surg. 2011 Apr;146(4):389-93. doi: 10.1001/archsurg.2011.29.
3
Anaphylaxis and other adverse reactions to blue dyes: a case series.对蓝色染料的过敏反应及其他不良反应：病例系列
Anaesth Intensive Care. 2011 Mar;39(2):287-92. doi: 10.1177/0310057X1103900221.
4
Sentinel lymph node biopsy in breast cancer: an analysis of the maximum number of nodes requiring excision.乳腺癌前哨淋巴结活检：分析需要切除的最大淋巴结数量。
Breast J. 2011 Jan-Feb;17(1):3-8. doi: 10.1111/j.1524-4741.2010.01019.x. Epub 2010 Dec 6.
5
Anaphylactic response to blue dye during sentinel lymph node biopsy.在进行前哨淋巴结活检时对蓝色染料发生过敏反应。
Surg Oncol. 2011 Mar;20(1):e55-9. doi: 10.1016/j.suronc.2010.10.002. Epub 2010 Nov 11.
6
Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial.前哨淋巴结切除术与乳腺癌临床淋巴结阴性患者常规腋窝淋巴结清扫术的比较：来自 NSABP B-32 随机 3 期试验的总生存结果。
Lancet Oncol. 2010 Oct;11(10):927-33. doi: 10.1016/S1470-2045(10)70207-2.
7
Does blue dye contribute to success of sentinel node mapping for breast cancer?蓝色染料是否有助于乳腺癌前哨淋巴结定位的成功？
Ann Surg Oncol. 2010 Oct;17 Suppl 3(0 3):280-5. doi: 10.1245/s10434-010-1235-5. Epub 2010 Sep 19.
8
Sentinel-lymph-node-based management or routine axillary clearance? One-year outcomes of sentinel node biopsy versus axillary clearance (SNAC): a randomized controlled surgical trial.基于前哨淋巴结的管理还是常规腋窝清扫？前哨淋巴结活检与腋窝清扫（SNAC）的一年结局：一项随机对照外科试验。
Ann Surg Oncol. 2009 Feb;16(2):266-75. doi: 10.1245/s10434-008-0229-z. Epub 2008 Dec 3.
9
The use of radioisotope combined with isosulfan Blue dye is not superior to radioisotope alone for the identification of sentinel lymph nodes in patients with breast cancer.对于乳腺癌患者，放射性同位素联合异硫蓝染料用于前哨淋巴结识别并不优于单独使用放射性同位素。
Surgery. 2008 Oct;144(4):606-9; discussion 609-10. doi: 10.1016/j.surg.2008.06.023.
10
Factors affecting failed localisation and false-negative rates of sentinel node biopsy in breast cancer--results of the ALMANAC validation phase.影响乳腺癌前哨淋巴结活检定位失败率和假阴性率的因素——ALMANAC验证阶段的结果
Breast Cancer Res Treat. 2006 Sep;99(2):203-8. doi: 10.1007/s10549-006-9192-1. Epub 2006 Mar 16.

蓝色染料在乳腺癌前哨淋巴结检测中的作用：对203例患者的回顾性研究

The Role of Blue Dye in Sentinel Node Detection for Breast Cancer: A Retrospective Study of 203 Patients.

作者信息

Garbay Jean-Remi, Skalli-Chrisostome Dounia, Leymarie Nicolas, Sarfati Benjamin, Rimareix Francoise, Mazouni Chafika

机构信息

Institut Gustave Roussy, Villejuif, France.

出版信息

Breast Care (Basel). 2016 Apr;11(2):128-32. doi: 10.1159/000445368. Epub 2016 Apr 26.

DOI:10.1159/000445368
PMID:27239175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4881247/
Abstract

OBJECTIVE

We aimed at examining the potential benefits of blue dye in sentinel node biopsy (SNB) in comparison with its proven drawbacks.

PATIENTS AND METHODS

In 2007, 203 T1 primary breast carcinomas had been operated on in our institute. The patients had undergone a lumpectomy and SNB. Sentinel node (SN) detection was exclusively isotopic (ISO) in 77 patients and performed with blue dye combined with a radioactive isotope (COMBI) in 126 patients. We compared the number of SNs and the rate of SN positivity in both groups.

RESULTS

The detection rate was 99% in both groups: 76/77 in the ISO group and 125/126 in the COMBI group. The mean number of SNs was 2.14 and 1.91 in the ISO group and the COMBI group, respectively (difference not significant (NS)). SN positivity was found in 26.1% and 24.6% in the ISO group and the COMBI group, respectively (NS). Only 1 SN had been removed in 26% of the patients in the ISO group versus 45.2% of the patients in the COMBI group (p = 0.004). No significant differences were observed in the tumor characteristics.

CONCLUSION

The systematic use of patent blue dye combined with isotopic detection does not appear to increase the overall performance of the SNB technique in this retrospective study.

摘要

目的

我们旨在研究蓝色染料在前哨淋巴结活检（SNB）中的潜在益处，并与其已证实的缺点进行比较。

患者与方法

2007年，我院对203例T1期原发性乳腺癌患者进行了手术。患者均接受了肿块切除术和前哨淋巴结活检。77例患者仅采用同位素（ISO）检测前哨淋巴结（SN），126例患者采用蓝色染料联合放射性同位素（COMBI）检测。我们比较了两组的SN数量和SN阳性率。

结果

两组的检测率均为99%：ISO组为76/77，COMBI组为125/126。ISO组和COMBI组的SN平均数量分别为2.14和1.91（差异无统计学意义（NS））。ISO组和COMBI组的SN阳性率分别为26.1%和24.6%（NS）。ISO组26%的患者仅切除了1个SN，而COMBI组为45.2%的患者（p = 0.004）。在肿瘤特征方面未观察到显著差异。

结论

在这项回顾性研究中，系统性地使用专利蓝色染料联合同位素检测似乎并未提高SNB技术的整体性能。