de Vries Nienke M, Staal J Bart, van der Wees Philip J, Adang Eddy M M, Akkermans Reinier, Olde Rikkert Marcel G M, Nijhuis-van der Sanden Maria W G
Radboud University Medical Center 114 IQ healthcare, PO Box 9101 6500 HB Nijmegen The Netherlands.
Radboud University Medical Center 114 IQ healthcare, PO Box 9101 6500 HB Nijmegen The Netherlands; Department of Musculoskeletal Rehabilitation HAN University of Applied Sciences Nijmegen The Netherlands.
J Cachexia Sarcopenia Muscle. 2016 Sep;7(4):422-35. doi: 10.1002/jcsm.12091. Epub 2015 Dec 4.
Despite the well-known health benefits of physical activity, it is a great challenge to stay physically active for frail-older adults with mobility limitations. The aim of this study was to test the (cost-) effectiveness of a patient-centred physical therapy strategy (Coach2Move) in which individualized treatment (motivational interviewing, physical examination, individualized goal setting, coaching and advice on self management, and physical training) is combined to increase physical activity level and physical fitness and, thereby, to decrease the level of frailty.
A randomized controlled trial was performed in 13 physical therapy practices with measurements at 3 and 6 months. Eligible patients were aged 70 years or over and had mobility problems (i.e. difficulties with walking, moving, getting up and changing position from bed or chair to standing, or stair climbing). The primary outcome was physical activity (total and moderate intensity) in minutes per day. Secondary outcomes were as follows: frailty, walking speed and distance, mobility, and quality of life. Data were analysed using linear mixed models for repeated measurements. Healthcare costs and quality-adjusted life years (QALYs) were computed and combined using net monetary benefit (NMB) for different willingness to pay thresholds. Data on costs, QALYs, and NMBs were analysed using linear mixed models.
One hundred and thirty patients participated in this study. At 6 months, the between-group difference was significant for moderate-intensity physical activity in favour of the Coach2Move group [mean difference: 17.9 min per day; 95% confidence interval (CI) 4.0 to 34.9; P = 0.012]. The between-group difference for total physical activity was 14.1 min per day (95% CI -6.6 to 34.9; P = 0.182). Frailty decreased more in the Coach2Move group compared with usual care [mean difference: -0.03 (95% CI: -0.06 to -0.00; P = 0.027)]. Compared with usual treatment, the Coach2Move strategy resulted in cost savings (€849.8; 95% CI: 1607 to 90; P = 0.028), an improvement in QALYs, (0.02; 95% CI: 0.00 to 0.03; P = 0.03), and a higher NMB at every willingness to pay threshold.
Older adults with mobility problems are able to safely increase physical activity in their own environment and reduce frailty. This study emphasizes both the potential cost-effectiveness of a patient-centred approach in the frail elderly and the importance of physical activity promotion in older adults with mobility limitations.
尽管体育活动对健康有益已广为人知,但对于行动不便的体弱老年人来说,保持身体活跃仍是一项巨大挑战。本研究的目的是测试一种以患者为中心的物理治疗策略(Coach2Move)的(成本)效益,该策略将个性化治疗(动机访谈、体格检查、个性化目标设定、自我管理指导与建议以及体育训练)相结合,以提高身体活动水平和身体素质,从而降低衰弱程度。
在13个物理治疗机构进行了一项随机对照试验,在3个月和6个月时进行测量。符合条件的患者年龄在70岁及以上,存在行动问题(即行走、移动、起床以及从床上或椅子上起身站立或爬楼梯困难)。主要结局是每天的身体活动量(总量和中等强度),以分钟为单位。次要结局如下:衰弱、步行速度和距离、行动能力以及生活质量。使用线性混合模型对重复测量数据进行分析。计算医疗保健成本和质量调整生命年(QALY),并使用净货币效益(NMB)针对不同的支付意愿阈值进行合并。使用线性混合模型分析成本、QALY和NMB的数据。
130名患者参与了本研究。在6个月时,中等强度身体活动的组间差异对Coach2Move组有利[平均差异:每天17.9分钟;95%置信区间(CI)4.0至34.9;P = 0.012]。总身体活动的组间差异为每天14.1分钟(95% CI -6.6至34.9;P = 0.182)。与常规护理相比,Coach2Move组的衰弱程度下降得更多[平均差异:-0.03(95% CI:-0.06至-0.00;P = 0.027)]。与常规治疗相比,Coach2Move策略节省了成本(849.8欧元;95% CI:1607至90;P = 0.028),QALY有所改善(0.02;95% CI:0.00至0.03;P = 0.03),并且在每个支付意愿阈值下NMB都更高。
有行动问题的老年人能够在自身环境中安全地增加身体活动并减轻衰弱程度。本研究强调了以患者为中心的方法在体弱老年人中的潜在成本效益以及在行动不便的老年人中促进身体活动的重要性。