Tyas M J
J Dent Res. 1977 Oct;56(10):1285-90. doi: 10.1177/00220345770560103401.
An vitro method of toxicity testing of dental restorative materials is described in which their clinical usage is closely simulated. The test material was separated from the cells by either a synthetic filter or dentine slice. Toxic effects were quantiated by determining changes in enzyme activity by scanning and integrating microdensitometry.
本文描述了一种牙科修复材料毒性测试的体外方法,该方法紧密模拟了它们的临床使用情况。测试材料通过合成滤膜或牙本质切片与细胞分离。通过扫描和积分显微密度测定法测定酶活性的变化来量化毒性作用。