Grunow J E, al-Hafidh A, Tunell W P
Department of Pediatrics, Oklahoma City, OK.
J Pediatr Surg. 1989 Jan;24(1):42-4; Discussion 44-5. doi: 10.1016/s0022-3468(89)80298-2.
The frequency and clinical significance of gastroesophageal reflux (GER) in patients after percutaneous endoscopic gastrostomy (PEG) was determined. Ten children, aged 11 months to 15 years, who had normal preoperative extended esophageal pH monitoring were restudied after PEG. Of the ten patients, six developed GER with a pH score significantly higher than their initial one (40.5 +/- 3.3 pre-PEG v 129.5 +/- 24.2 post-PEG, P less than .005). Similarly, the mean post-PEG pH score was higher in patients with GER than in those without a change in score (129.5 +/- 24.2 v 33.8 +/- 2.8, P less than .005). None of these patients was symptomatic for GER immediately after the PEG, but within 10 months of surgery, three of six (50%) developed reflux-related symptoms. These data indicate that clinically significant GER is associated with PEG.
确定经皮内镜下胃造口术（PEG）后患者胃食管反流（GER）的频率及其临床意义。对10名年龄在11个月至15岁之间、术前食管pH值监测正常的儿童在PEG术后再次进行研究。这10名患者中，6名出现GER，其pH评分显著高于初始评分（PEG术前为40.5±3.3，PEG术后为129.5±24.2，P<0.005）。同样，有GER的患者PEG术后平均pH评分高于评分无变化的患者（129.5±24.2对33.8±2.8，P<0.005）。这些患者在PEG术后即刻均无GER相关症状，但在术后10个月内，6名患者中有3名（50%）出现了反流相关症状。这些数据表明，具有临床意义的GER与PEG相关。
