Department of Chemistry, East Tennessee State University, Johnson City, TN 37614, USA.
Nanotechnology. 2016 Jul 15;27(28):284002. doi: 10.1088/0957-4484/27/28/284002. Epub 2016 Jun 2.
While 3D printing technologies first appeared in the 1980s, prohibitive costs, limited materials, and the relatively small number of commercially available printers confined applications mainly to prototyping for manufacturing purposes. As technologies, printer cost, materials, and accessibility continue to improve, 3D printing has found widespread implementation in research and development in many disciplines due to ease-of-use and relatively fast design-to-object workflow. Several 3D printing techniques have been used to prepare devices such as milli- and microfluidic flow cells for analyses of cells and biomolecules as well as interfaces that enable bioanalytical measurements using cellphones. This review focuses on preparation and applications of 3D-printed bioanalytical devices.
虽然 3D 打印技术早在 20 世纪 80 年代就已出现,但由于成本过高、可用材料有限以及可供商业使用的打印机相对较少,其应用主要局限于制造目的的原型制作。随着技术、打印机成本、材料和可及性的不断提高,由于其易于使用和相对较快的设计到对象工作流程,3D 打印已在许多学科的研究和开发中得到广泛应用。已经使用了几种 3D 打印技术来制备微流控和毫流控流动池等设备,以分析细胞和生物分子以及实现使用手机进行生物分析测量的接口。本文综述了 3D 打印生物分析器件的制备和应用。