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化学与生物学领域的3D打印微型流体工具。

3D-printed miniaturized fluidic tools in chemistry and biology.

作者信息

Dixit C K, Kadimisetty K, Rusling J

机构信息

Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, United States.

Institute of Materials Science, University of Connecticut, Storrs, CT 06269-3136, United States.

出版信息

Trends Analyt Chem. 2018 Sep;106:37-52. doi: 10.1016/j.trac.2018.06.013. Epub 2018 Jul 5.

Abstract

3D printing (3DP), an additive manufacturing (AM) approach allowing for rapid prototyping and decentralized fabrication on-demand, has become a common method for creating parts or whole devices. The wide scope of the AM extends from organized sectors of construction, ornament, medical, and R&D industries to individual explorers attributed to the low cost, high quality printers along with revolutionary tools and polymers. While progress is being made but big manufacturing challenges are still there. Considering the quickly shifting narrative towards miniaturized analytical systems (MAS) we focus on the development/rapid prototyping and manufacturing of MAS with 3DP, and application dependent challenges in engineering designs and choice of the polymeric materials and provide an exhaustive background to the applications of 3DP in biology and chemistry. This will allow readers to perceive the most important features of AM in creating (i) various individual and modular components, and (ii) complete integrated tools.

摘要

3D打印(3DP)是一种增材制造(AM)方法,可实现快速成型和按需分散制造,已成为制造零件或整个设备的常用方法。由于低成本、高质量的打印机以及革命性的工具和聚合物,增材制造的广泛范围从建筑、装饰、医疗和研发行业的有组织部门扩展到个人探索者。虽然正在取得进展,但仍然存在重大的制造挑战。考虑到对小型分析系统(MAS)的叙述迅速转变,我们专注于使用3DP开发/快速成型和制造MAS,以及工程设计和聚合物材料选择中与应用相关的挑战,并为3DP在生物学和化学中的应用提供详尽的背景。这将使读者能够了解增材制造在创建(i)各种单个和模块化组件以及(ii)完整集成工具方面的最重要特征。

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