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埃及青春期前儿童血清25-羟基维生素D与生活方式和饮食因素的关联

Association of Serum 25-Hydroxyvitamin D with Life Style and Dietary Factors in Egyptian Prepubescent Children.

作者信息

Shady Mones M Abu, Youssef Mai M, Shehata Manal A, El-Din Ebtissam M Salah, ElMalt Heba A

机构信息

Child Health Department, National Research Centre, Cairo, Egypt.

Medical Biochemistry Department, Medical Division, National Research Centre, Cairo, Egypt.

出版信息

Open Access Maced J Med Sci. 2015 Mar 15;3(1):80-4. doi: 10.3889/oamjms.2015.006. Epub 2015 Jan 1.

Abstract

BACKGROUND

There had been a growing evidence of high prevalence of vitamin D deficiency especially among children which may increase the risk of many chronic diseases in adulthood.

AIM

Assessment of different lifestyles and dietary behaviour influencing the level of serum 25-OHD in a group of Egyptian prepubescent children.

SUBJECTS AND METHODS

Two hundred boys and girls aged from 9 to 11 years were recruited from two primary public schools situated in Giza governorate in Egypt. A questionnaire was developed to obtain relevant information related to age, dietary habits, and physical activity. Thorough clinical examination and measurement of weight and height were performed. Body mass index was calculated. Serum samples were assayed for 25-hydroxy vitamin D (25-OHD).

RESULTS

Low serum 25-OHD (< 20 ng/ml) was found in 11.5% of the whole sample. Mean serum 25-OHD was significantly lower in obese subjects and in those with low physical activity (p < 0.05). Multiple stepwise linear regression analysis showed that BMI and physical activity were the main predictors of serum 25-OHD (P < 0.05).

CONCLUSIONS

Lifestyle factors in terms of physical activity and BMI may contribute significantly to the optimal vitamin D status of apparently healthy children.

摘要

背景

越来越多的证据表明维生素D缺乏症的高患病率,尤其是在儿童中,这可能会增加成年后患多种慢性病的风险。

目的

评估影响一组埃及青春期前儿童血清25-OHD水平的不同生活方式和饮食行为。

对象与方法

从埃及吉萨省的两所公立小学招募了200名9至11岁的男孩和女孩。设计了一份问卷以获取与年龄、饮食习惯和身体活动相关的信息。进行了全面的临床检查并测量了体重和身高。计算了体重指数。对血清样本进行25-羟基维生素D(25-OHD)检测。

结果

在整个样本中,11.5%的人血清25-OHD水平较低(<20 ng/ml)。肥胖受试者和身体活动量低的受试者的血清25-OHD平均水平显著较低(p<0.05)。多元逐步线性回归分析表明,体重指数和身体活动是血清25-OHD的主要预测因素(P<0.05)。

结论

就身体活动和体重指数而言,生活方式因素可能对看似健康的儿童的最佳维生素D状态有显著贡献。

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