Taniguchi Nobuyuki, Hayashida Naomi, Shimura Hiroki, Okubo Noriyuki, Asari Yasushi, Nigawara Takeshi, Midorikawa Sanae, Kotani Kazuhiko, Nakaji Shigeyuki, Imaizumi Misa, Ohtsuru Akira, Akamizu Takashi, Kitaoka Masafumi, Suzuki Shinichi, Yamashita Shunichi, Takamura Noboru
Department of Clinical Laboratory Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.
J Med Ultrason (2001). 2013 Jul;40(3):219-24. doi: 10.1007/s10396-013-0456-1. Epub 2013 May 18.
The Fukushima Health Management Survey conducted after the accident at the Fukushima Nuclear Power Plant included thyroid ultrasound examinations for children aged ≤18 years at the time of the accident. The purpose of this study was to investigate the frequency of thyroid nodular lesions detected using high-quality ultrasonography in a general population of Japanese children, in whom such data have not been previously characterized.
The current study investigated 4,365 free-living children aged between 3 and 18 years in three Japanese prefectures (Aomori, Yamanashi and Nagasaki). The same ultrasonography equipment as that used in the Fukushima Survey was employed to observe thyroid nodular lesions. The following categories of findings were used-'A', further examinations are not necessary; 'B', the presence of thyroid nodules with a diameter of ≥5.1 mm or thyroid cysts with a diameter of ≥20.1 mm; and 'C', immediate further examinations are required. As a sub-category of 'A', 'A1' was defined as the absence of nodules or cysts, and 'A2' was defined as the presence of thyroid nodules with a diameter of ≤5.0 mm or thyroid cysts with a diameter of ≤20.0 mm.
Overall, 4,321 (99 %) of the total participants were classified with a status of 'A' and 44 (1 %) were classified with a status of 'B'. No participants were classified with a status of 'C'. A total of 56.5 % of the total participants was classified with a status of 'A2'. Thyroid nodules were identified in 1.6 % of the total participants and thyroid cysts were identified in 56.9 % of the participants.
The current study provides data regarding the actual frequency of ultrasonographically detected thyroid nodular lesions among the Japanese children. These results would be useful for evaluating thyroid findings in Japanese children, although careful interpretation is required.
福岛核电站事故后开展的福岛健康管理调查对事故发生时年龄≤18岁的儿童进行了甲状腺超声检查。本研究的目的是调查在日本儿童普通人群中使用高质量超声检查检测到的甲状腺结节性病变的频率，此前此类数据尚无特征描述。
本研究调查了日本三个县（青森、山梨和长崎）的4365名3至18岁的自由生活儿童。使用与福岛调查相同的超声检查设备观察甲状腺结节性病变。采用以下检查结果分类——“A”，无需进一步检查；“B”，存在直径≥5.1毫米的甲状腺结节或直径≥20.1毫米的甲状腺囊肿；“C”，需要立即进一步检查。作为“A”的子类别，“A1”定义为无结节或囊肿，“A2”定义为存在直径≤5.0毫米的甲状腺结节或直径≤20.0毫米的甲状腺囊肿。
总体而言，4321名（99%）参与者被分类为“A”状态，44名（1%）被分类为“B”状态。没有参与者被分类为“C”状态。共有56.5%的参与者被分类为“A2”状态。在1.6%的参与者中发现了甲状腺结节，在56.9%的参与者中发现了甲状腺囊肿。
本研究提供了关于日本儿童中超声检查检测到的甲状腺结节性病变实际频率的数据。尽管需要谨慎解读，但这些结果将有助于评估日本儿童的甲状腺检查结果。
