卧床休息和干浸期间作为应对措施的离心法：我们学到了什么？
Centrifugation as a countermeasure during bed rest and dry immersion: What has been learned?
作者信息
Clément G, Paloski W H, Rittweger J, Linnarsson D, Bareille M P, Mulder E, Wuyts F L, Zange J
机构信息
Lyon Neuroscience Research Center, Bron, France.
出版信息
J Musculoskelet Neuronal Interact. 2016 Jun 7;16(2):84-91.
Abstract
OBJECTIVES
We review the studies that have evaluated intermittent short-radius centrifugation as a potential countermeasure for cardiovascular, musculoskeletal, and sensorimotor deconditioning in simulated weightlessness.
METHODS
The findings from 18 experimental protocols that have used bed rest and dry immersion for comparing the protective effects of centrifugation versus standing upright or walking, and the effects of continuous vs. periodic exposure to centrifugation are discussed.
RESULTS
Centrifugation for as little as 30 min per day was found to be effective in mitigating orthostatic intolerance and strength in postural muscle after 5 days of bed rest, but it was not effective in mitigating plasma volume loss.
CONCLUSION
To determine the optimal prescription for centrifugation as a countermeasure, we recommend further studies using (a) bed rest of longer duration, (b) individualized prescriptions of centrifugation combined with exercise, and
摘要
目的
我们回顾了一些研究，这些研究评估了间歇性短半径离心作为模拟失重状态下心血管、肌肉骨骼和感觉运动功能失调的一种潜在对策。
方法
讨论了18个实验方案的结果，这些方案使用卧床休息和干浸来比较离心与直立或行走的保护效果，以及持续与定期暴露于离心的效果。
结果
发现每天仅进行30分钟的离心在减轻卧床休息5天后的体位性不耐受和姿势肌肉力量方面是有效的，但在减轻血浆量损失方面无效。
结论
为了确定作为对策的离心的最佳方案，我们建议进一步开展研究，采用（a）持续时间更长的卧床休息，（b）结合运动的个性化离心方案，以及
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