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人体测量学特征波动不对称性的遗传方差研究。

Study of genetic variance in the fluctuating asymmetry of anthropometrical traits.

作者信息

Livshits G, Kobyliansky E

机构信息

Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Israel.

出版信息

Ann Hum Biol. 1989 Mar-Apr;16(2):121-9. doi: 10.1080/03014468700006972.

DOI:10.1080/03014468700006972
PMID:2729889
Abstract

We have studied the fluctuating asymmetry (FA) of 8 bilateral morphometric traits in two-parent families, comprising 216 families with one newborn baby, and 60 families with two children (age range 5-18 years). Heritability was assessed by: (1) multiple regression analyses of the children's measurements on the mother's and father's measurements; (2) midparent-child regressions; and (3) sibling correlations. The extent of genetic determination of individual FA measurements was generally low, albeit statistically significant in some cases. However, even these correlations were inconsistent between samples and relatives. However, the mean FA values for all 8 studied traits showed positive and significant correlation between parents and children in two samples and in total. Additive genetic variance, calculated from multiple regression analyses and midparent-child correlations, was estimated to be between 0.25-0.30. Three multiple regressions (two for the separate group and one for the total sample) yielded a statistically significant value (between 0.21-0.33) also for the non-additive genetic component.

摘要

我们研究了双亲家庭中8种双侧形态测量性状的波动不对称性(FA),其中包括216个有一名新生儿的家庭以及60个有两个孩子(年龄在5至18岁之间)的家庭。通过以下方式评估遗传力:(1)对孩子的测量值与母亲和父亲的测量值进行多元回归分析;(2)中亲-子女回归;以及(3)同胞相关性分析。个体FA测量值的遗传决定程度总体较低,尽管在某些情况下具有统计学意义。然而,即使这些相关性在样本和亲属之间也不一致。不过,在两个样本以及总体中,所研究的全部8个性状的平均FA值在父母与子女之间均呈现出显著的正相关。通过多元回归分析和中亲-子女相关性计算得出的加性遗传方差估计在0.25至0.30之间。三项多元回归分析(两项针对单独分组,一项针对总样本)得出非加性遗传成分的统计学显著值(在0.21至0.33之间)。

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