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具有高风险特征的头皮汗孔癌经手术及辅助放疗治疗:一例病例报告并文献复习

Porocarcinoma scalp with high risk features treated with surgery and adjuvant radiotherapy: A case report and review of literature.

作者信息

Melgandi Wineeta, Benson Rony, Hakin Abdul, Bhasker Suman

机构信息

Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.

Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.

出版信息

J Egypt Natl Canc Inst. 2016 Sep;28(3):195-8. doi: 10.1016/j.jnci.2016.05.004. Epub 2016 Jun 11.

Abstract

Eccrine porocarcinoma is a rare malignant sweat gland tumor arising from the intra dermal part of the gland and accounts for only 0.005% of all epithelial cutaneous tumors. Commonly involved site includes extremities and face. Scalp is a rare site for porocarcinoma with less than 20 reported cases so far. Wide local excision with clear margins remains the treatment of choice. Review of literature revealed a local recurrence rate of 37.5% and a nodal involvement risk of 20%. Porocarcinoma of the scalp is peculiar in that the primary tumor may be large at presentation, making surgery with adequate margins difficult. Adjuvant radiotherapy must be considered in a case to case basis due to the high local recurrence rates compared to other sites of porocarcinoma and should be given to all patients with close margins and extra capsular extension.

摘要

小汗腺癌是一种罕见的恶性汗腺肿瘤,起源于汗腺的真皮内部分,仅占所有上皮性皮肤肿瘤的0.005%。常见受累部位包括四肢和面部。头皮是小汗腺癌的罕见部位,迄今为止报道的病例少于20例。手术切缘清晰的广泛局部切除仍然是首选治疗方法。文献回顾显示局部复发率为37.5%,淋巴结受累风险为20%。头皮小汗腺癌的特殊之处在于,原发肿瘤在就诊时可能很大,使得获得足够切缘的手术变得困难。由于与其他部位的小汗腺癌相比局部复发率较高,因此必须根据具体情况考虑辅助放疗,对于所有切缘接近和有包膜外扩展的患者均应给予放疗。

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