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[甲状旁腺实质和间质中的细胞更新]

[Cellular renewal in the parenchyma and stroma of the parathyroid glands].

作者信息

Pavlov A V, Zapriagaev V V

出版信息

Arkh Anat Gistol Embriol. 1989 Jan;96(1):78-81.

PMID:2730362
Abstract

By means of autoradiographic, morphometric and cytophotometric methods main parameters, characterizing processes of cellular renewal have been studied in the parathyroid glands of 66 mature white male rats with body mass of 160-230 g. The time of renewal of the parathyrocyte population is 80-100 days, the average daily mitotic index--0.88 +/- 0.09% 0, the average duration of mitosis--1.61 h, the average daily index of dying cells--0.24 +/- 0.03% 0. The greatest mitotic activity of parathyrocytes is revealed in the evening and early in the morning. At night together with decreasing amount of dividing cells, content of dying parathrocytes increases. The glandular cell population is mainly diploid, polyploid cells make no more than 0.1%. The time of renewal of stromal cells makes 82 +/- 9 days. The results obtained demonstrate that the parathyroid cells should be considered as a slowly renewal population.

摘要

采用放射自显影、形态测量和细胞光度测量方法,对66只体重160 - 230克的成熟雄性白色大鼠甲状旁腺中表征细胞更新过程的主要参数进行了研究。甲状旁腺细胞群的更新时间为80 - 100天,平均每日有丝分裂指数为0.88±0.09%,平均有丝分裂持续时间为1.61小时,平均每日死亡细胞指数为0.24±0.03%。甲状旁腺细胞的最大有丝分裂活性出现在傍晚和清晨。夜间,随着分裂细胞数量的减少,死亡甲状旁腺细胞的含量增加。腺细胞群主要为二倍体,多倍体细胞不超过0.1%。基质细胞的更新时间为82±9天。所得结果表明,甲状旁腺细胞应被视为更新缓慢的细胞群。

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