Pavlov A V
Arkh Anat Gistol Embriol. 1986 Sep;91(9):77-80.
By means of morphometrical methods, as well as by the method of volumetric reconstruction of the organs in 33 rats during 1-30 days regeneration of parathyroid glands have been studied after a simultaneous resection of the whole left and a half of the right gland. Total calcium content in blood serum in the experimental animals decreases on the 1st-2d day and normalizes by the 3d day. Regeneration of the remained part of the gland is realized at the expense of increasing mitotic activity and hypertrophy of parathyrocytes along the whole organ from the 3d up to the 13th day. There are no signs of the glandular parenchyma growth from the wound surface. On the 3d-5th day dividing parathyrocytes predominate in the half of the gland that adjoins the wound. This promotes a predominant longitudinal growth of the gland remnant and restoration of the organ's ellipsoid form on the 20th-30th day. The main pattern of the parathyroid gland restoration after its partial resection is regenerative hypertrophy.
通过形态测量方法以及器官体积重建方法,在33只大鼠中研究了在同时切除整个左甲状旁腺和右甲状旁腺一半后1 - 30天甲状旁腺的再生情况。实验动物血清总钙含量在第1 - 2天下降,并在第3天恢复正常。从第3天到第13天,腺体剩余部分的再生是通过有丝分裂活性增加和甲状旁腺细胞沿整个器官肥大来实现的。没有从伤口表面生长出腺实质的迹象。在第3 - 5天,靠近伤口的腺体一半中,正在分裂的甲状旁腺细胞占主导。这促进了腺体残余部分的主要纵向生长,并在第20 - 30天恢复器官的椭圆形形态。甲状旁腺部分切除后恢复的主要模式是再生性肥大。