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起源于细胞性蓝色痣的眼眶原发性恶性黑色素瘤。

Primary malignant melanoma of the orbit arising in a cellular blue naevus.

作者信息

Löffler K U, Witschel H

机构信息

Department of Ophthalmology, Freiburg University, FRG.

出版信息

Br J Ophthalmol. 1989 May;73(5):388-93. doi: 10.1136/bjo.73.5.388.

DOI:10.1136/bjo.73.5.388
PMID:2730864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1041749/
Abstract

Primary malignant melanoma of the orbit is a rare clinical entity. We report the clinical course and present the light and electron microscopic findings in a case arising in a cellular blue naevus. While most orbital melanomas are associated with a naevus of Ota, there was no clinically visible abnormal pigmentation in our patient. The possible origin of the tumour cell and its ultrastructural features are discussed.

摘要

眼眶原发性恶性黑色素瘤是一种罕见的临床病症。我们报告了一例起源于细胞性蓝色痣的病例的临床病程,并展示了其光镜和电镜检查结果。虽然大多数眼眶黑色素瘤与太田痣有关,但我们的患者并无临床上可见的色素沉着异常。本文讨论了肿瘤细胞的可能起源及其超微结构特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/f7737385e81d/brjopthal00597-0076-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/619ca1613be5/brjopthal00597-0073-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/a6292385bd20/brjopthal00597-0073-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/3c788b643e1d/brjopthal00597-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/cc796ade94a2/brjopthal00597-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/40338c017c63/brjopthal00597-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/b3ef922ade10/brjopthal00597-0075-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/b51e36870b40/brjopthal00597-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/f7737385e81d/brjopthal00597-0076-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/619ca1613be5/brjopthal00597-0073-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/a6292385bd20/brjopthal00597-0073-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/3c788b643e1d/brjopthal00597-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/cc796ade94a2/brjopthal00597-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/40338c017c63/brjopthal00597-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/b3ef922ade10/brjopthal00597-0075-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/b51e36870b40/brjopthal00597-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1628/1041749/f7737385e81d/brjopthal00597-0076-b.jpg

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本文引用的文献

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Orbital malignant melanoma and oculodermal melanocytosis: report of two cases and review of the literature.眼眶恶性黑色素瘤与眼皮肤黑素细胞增多症:2例报告及文献复习
Ophthalmology. 1984 May;91(5):497-507. doi: 10.1016/s0161-6420(84)34261-0.
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The ultrastructure of conjunctival melanocytic tumors.结膜黑素细胞肿瘤的超微结构
Trans Am Ophthalmol Soc. 1984;82:599-752.
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Malignant melanoma of the orbit arising in a nevus of Ota.起源于太田痣的眼眶恶性黑色素瘤。
原发性眼眶黑色素瘤:13例患者的临床表现、治疗及长期预后
Front Oncol. 2017 Dec 18;7:316. doi: 10.3389/fonc.2017.00316. eCollection 2017.
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An Orbital Malignant Melanoma Arising in Cellular Blue Nevus in a Patient with Nevus of Ota.一名患有太田痣的患者,其细胞性蓝痣发生眶部恶性黑色素瘤。
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