Falkensson M, Jones W, Sörbo B
Department of Clinical Chemistry, Faculty of Health Sciences, Linköping University Hospital, Sweden.
Clin Chem. 1989 Jun;35(6):918-21.
We describe a novel mouth-cup device for sampling breath from unconscious subjects and analysis with a hand-held breath-alcohol instrument, the "Alcolmeter SD-2." This equipment was evaluated in healthy volunteers after they drank a moderate dose of alcohol. Three kinds of breath were analyzed: (a) end-expired air from a conventional mouth-tube, (b) breath sampled from the mouth-cup, and (c) air from a nasal tube supplied with the breath analyzer. The ethanol concentration in breath from the mouth-cup was slightly less than in end-expired air but significantly greater than in nasal air. Results with mouth-tube and mouth-cup correlated highly with blood-ethanol concentration as determined by gas chromatography; nasal-tube air correlated less well. The Alcolmeter responded not only to ethanol but also to methanol, 1-propanol, and 2-propanol, whereas ethylene glycol gave no response. The time-response curve for methanol was different, and this might permit differential diagnosis of methanol poisoning.
我们描述了一种新型口杯装置，用于从不省人事的受试者采集呼气样本，并使用手持式呼气酒精检测仪“Alcolmeter SD - 2”进行分析。该设备在健康志愿者饮用适量酒精后进行了评估。分析了三种呼气：(a) 来自传统口管的终末呼气，(b) 从口杯采集的呼气，以及 (c) 由呼气分析仪配备的鼻管采集的空气。口杯呼气中的乙醇浓度略低于终末呼气，但显著高于鼻内空气。口管和口杯的结果与气相色谱法测定的血液乙醇浓度高度相关；鼻管空气的相关性较差。Alcolmeter不仅对乙醇有反应，对甲醇、1 - 丙醇和2 - 丙醇也有反应，而乙二醇无反应。甲醇的时间反应曲线不同，这可能有助于甲醇中毒的鉴别诊断。
