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基于中医辨证的代谢综合征的中医治疗:以舌诊为预测指标

Traditional Chinese Medicine for Metabolic Syndrome via TCM Pattern Differentiation: Tongue Diagnosis for Predictor.

作者信息

Lee Tsung-Chieh, Lo Lun-Chien, Wu Fang-Chen

机构信息

Department of Traditional Chinese Medicine, Changhua Christian Hospital, Changhua 500, Taiwan.

Department of Traditional Chinese Medicine, Changhua Christian Hospital, Changhua 500, Taiwan; Graduate Institute of Statistics and Information Science, National Changhua University of Education, Changhua 500, Taiwan.

出版信息

Evid Based Complement Alternat Med. 2016;2016:1971295. doi: 10.1155/2016/1971295. Epub 2016 May 25.

Abstract

Metabolic syndrome is a morbid condition, which is manifested by central obesity, abnormal glucose tolerance, lipodystrophy, and hypertension. Traditional Chinese medicine (TCM) clarifies that obesity is classified as phlegm-dampness. It is often accompanied with qi stagnation and blood stasis. One hundred and two overweight adults, who did not receive lipid-lowering drugs, were enrolled for analysis. The exclusion criteria were adults having malignancy disease, DM, and renal disease or who were pregnant or lactating. The study was divided into two groups: metabolic syndrome group (MetS) and nonmetabolic syndrome group (nMetS). The modern tongue analysis and heart rate variability devices for data analysis and Council on Nutrition Appetite Questionnaire (CNAQ) for appetite evaluation were used. Obesity patients with metabolic syndrome obviously have lower CNAQ score. The 6 items of CNAQ between two groups have significant difference in variation (P < 0.001). The nMetS average was above 28 scores (96%) and the MetS was all in 17-28 scores. The tongue appearance showed that MetS group have white coating different from the nMetS group with white and yellow coating (P < 0.05). However the HRV is not different from nMetS group significantly. Our results try to explore the relationship between the TCM pattern, nutrition appetite, and heart rate variability in metabolic syndrome patients.

摘要

代谢综合征是一种病态,表现为中心性肥胖、糖耐量异常、脂肪代谢障碍和高血压。中医认为肥胖属于痰湿范畴,常伴有气滞血瘀。本研究纳入了102名未服用降脂药物的超重成年人进行分析。排除标准为患有恶性疾病、糖尿病、肾脏疾病的成年人,以及孕妇或哺乳期妇女。研究分为两组:代谢综合征组(MetS)和非代谢综合征组(nMetS)。使用现代舌象分析和心率变异性设备进行数据分析,并使用营养食欲问卷委员会(CNAQ)进行食欲评估。患有代谢综合征的肥胖患者的CNAQ评分明显较低。两组之间CNAQ的6个项目在变异性上有显著差异(P < 0.001)。nMetS组的平均分在28分以上(96%),而MetS组的分数均在17 - 28分之间。舌象显示,MetS组的舌苔为白色,与nMetS组的白黄相间舌苔不同(P < 0.05)。然而,MetS组的心率变异性与nMetS组相比无显著差异。我们的研究结果试图探讨代谢综合征患者的中医证型、营养食欲和心率变异性之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab0/4897669/4b7909a58199/ECAM2016-1971295.001.jpg

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