Huang Yung-Sheng, Wu Han-Kuei, Chang Hen-Hong, Lee Tsung-Chieh, Huang Sung-Yen, Chiang John Y, Hsu Po-Chi, Lo Lun-Chien
School of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan.
Department of Chinese Medicine, YuanRung Hospital, Yuanlin City, Changhua County, 510, Taiwan.
J Tradit Complement Med. 2022 Apr 7;12(5):505-510. doi: 10.1016/j.jtcme.2022.04.001. eCollection 2022 Sep.
Stroke is a major cause of disability worldwide, and ischemic stroke is the most common type of stroke. The prevention and treatment of ischemic stroke remain a challenge worldwide. Traditional Chinese medicine (TCM) is often sought to provide an alternative therapy for the prevention and rehabilitation intervention of ischemic stroke in Taiwan. Therefore, this study explored the pivotal variables of tongue diagnosis among acute ischemic stroke and healthy participants in middle and older age.
This was a cross-sectional and case-controlled study. Data were collected from 99 patients with acute ischemic stroke and 286 healthy participants who received tongue diagnoses at Changhua Christian Hospital (CCH) from September 1, 2014, to December 31, 2016. Tongue features were extracted using the automatic tongue diagnosis system. Nine tongue features, including tongue shape, tongue color, fur thickness, fur color, saliva, tongue fissures, ecchymoses, teeth marks, and red spots were analyzed.
Objective image analysis techniques were used to identify significant differences in the many tongue features between patients with acute ischemic stroke and individuals without stroke. According to the logistic regression analysis, pale tongue color (OR:5.501, = 0.001), bluish tongue color (OR:4.249, = 0.014), ecchymoses (OR:1.058, < 0.001), and tongue deviation angle (OR:1.218, < 0.001) were associated with significantly increased odds ratios for acute ischemic stroke. The research revealed that tongue feature abnormalities were significantly related to the occurrence of ischemic stroke.
中风是全球致残的主要原因，缺血性中风是最常见的中风类型。缺血性中风的预防和治疗在全球范围内仍是一项挑战。在台湾，人们常常寻求中医为缺血性中风的预防和康复干预提供替代疗法。因此，本研究探讨了中老年急性缺血性中风患者和健康参与者舌诊的关键变量。
这是一项横断面病例对照研究。收集了2014年9月1日至2016年12月31日在彰化基督教医院接受舌诊的99例急性缺血性中风患者和286例健康参与者的数据。使用自动舌诊系统提取舌象特征。分析了九个舌象特征，包括舌形、舌色、苔厚、苔色、唾液、舌裂、瘀斑、齿痕和红点。
采用客观图像分析技术，识别急性缺血性中风患者与非中风个体在许多舌象特征上的显著差异。根据逻辑回归分析，淡舌色（比值比：5.501，P = 0.001）、青紫舌色（比值比：4.249，P = 0.014）、瘀斑（比值比：1.058，P < 0.001）和舌偏斜角度（比值比：1.218，P < 0.001）与急性缺血性中风的比值比显著增加相关。研究表明，舌象特征异常与缺血性中风的发生显著相关。
