Hawkes C H, Goldblatt P O, Shewry M, Fox A J
Department of Neurology, Ipswich Hospital, London, UK.
J Neurol Neurosurg Psychiatry. 1989 May;52(5):618-21. doi: 10.1136/jnnp.52.5.618.
A case-control approach was used to study the relationship between parental age and motor neuron disease (MND) in a nationally representative sample of men. [The method, involving a search for parents' records in the NHS Central Register, is new and may be of interest in other conditions where parental age is thought to play a part.] The parents of men who died of MND in 1979 were not older than the parents of sex, age and regionally standardised controls who died in the same year.
采用病例对照研究方法,对全国具有代表性的男性样本进行研究,以探讨父母年龄与运动神经元病(MND)之间的关系。[该方法包括在英国国家医疗服务体系中央登记处查找父母的记录,此方法新颖,在其他认为父母年龄可能起作用的疾病研究中可能会引起关注。]1979年死于运动神经元病的男性的父母,并不比同年死亡的、按性别、年龄和地区标准化后的对照组的父母年龄更大。