Gunnarsson L G, Lindberg G, Söderfelt B, Axelson O
Department of Neurology, Orebro Medical Center Hospital, Sweden.
Arch Neurol. 1990 Jan;47(1):42-6. doi: 10.1001/archneur.1990.00530010050018.
The age-standardized mortality from motor neuron disease in Sweden doubled from 1961 to 1985. The average annual rate during the period was 1.9 per 100,000 population. The male to female ratio was 1.2:1. The age-specific mortality rates had a peak at 70 to 79 years of age. When each birth cohort was followed up separately over time, the peak was less clear and in some cohorts the mortality rates increased continuously with advancing age. A significant increase of motor neuron disease among men was found in one Swedish county.
1961年至1985年期间,瑞典运动神经元病的年龄标准化死亡率翻了一番。该时期的年均死亡率为每10万人口1.9例。男女比例为1.2:1。年龄别死亡率在70至79岁达到峰值。当分别对每个出生队列进行长期随访时,峰值不太明显,在一些队列中,死亡率随着年龄增长持续上升。在瑞典的一个县发现男性运动神经元病显著增加。