改良 Hodge 试验、Carba NP 试验和碳青霉烯灭活法作为产碳青霉烯酶肠杆菌科细菌筛选方法的比较
Comparison of the Modified-Hodge test, Carba NP test, and carbapenem inactivation method as screening methods for carbapenemase-producing Enterobacteriaceae.
作者信息
Yamada Kageto, Kashiwa Machiko, Arai Katsumi, Nagano Noriyuki, Saito Ryoichi
机构信息
Department of Clinical Laboratory, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital, Tokyo, Japan.
Department of Clinical Laboratory, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital, Tokyo, Japan.
出版信息
J Microbiol Methods. 2016 Sep;128:48-51. doi: 10.1016/j.mimet.2016.06.019. Epub 2016 Jun 18.
We compared three screening methods for carbapenemase-producing Enterobacteriaceae. While the Modified-Hodge test and Carba NP test produced false-negative results for OXA-48-like and mucoid NDM producers, the carbapenem inactivation method (CIM) showed positive results for these isolates. Although the CIM required cultivation time, it is well suited for general clinical laboratories.
我们比较了三种用于检测产碳青霉烯酶肠杆菌科细菌的筛查方法。改良 Hodge 试验和 Carba NP 试验对产 OXA-48 样酶和黏液型 NDM 的菌株产生了假阴性结果，而碳青霉烯灭活法（CIM）对这些分离株显示出阳性结果。虽然 CIM 需要培养时间，但它非常适合一般临床实验室。
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