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杜氏肌营养不良症功能评估量表上下楼梯域的反应性:一年随访。

Responsiveness of the domain climbing up and going down stairs of the Functional Evaluation scale for Duchenne Muscular Dystrophy: a one-year follow-up.

机构信息

Programa de Pós-graduação em Ciências da Reabilitação, Laboratório de Fisioterapia e Comportamento, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil.

出版信息

Braz J Phys Ther. 2016 Jun 16;20(5):471-476. doi: 10.1590/bjpt-rbf.2014.0178.

DOI:10.1590/bjpt-rbf.2014.0178
PMID:27333479
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5123265/
Abstract

OBJECTIVE

: To determine the responsiveness of the domain climbing up and going down stairs of the Functional Evaluation Scale for Duchenne Muscular Dystrophy (FES-DMD-D3) in a one-year follow-up study.

METHOD

: The study included 26 patients with DMD. Effect Size (ES) and Standardized Response Mean (SRM) described the scale's responsiveness.

RESULTS

: For climbing up stairs, ES showed that responsiveness was low in the three-month assessments (0.26; 0.35; 0.13; 0.17), low to moderate in the six-month assessments (0.58; 0.48; 0.33), moderate in the nine-month assessments (0.70; 0.68), and high in the 12-month assessment (0.88). SRM showed that responsiveness was low in the three-month assessments (0.29; 0.38; 0.18; and 0.19), low to moderate in the six-month assessments (0.59; 0.51; 0.36), moderate in the nine-month assessments (0.74 and 0.70), and high in the 12-month assessment (0.89). For going down stairs, ES showed that responsiveness was low in the three- and six-month assessments (0.16; 0.25; 0.09; 0.08 and 0.48; 0.35; 0.18, respectively), low to moderate in the nine-month assessments (0.59; 0.44), and moderate in the 12-month assessment (0.71). SRM showed that responsiveness was low in the three- and six-month assessments (0.25; 0.35; 0.12; 0.09 and 0.47; 0.38; 0.21, respectively), low to moderate in the nine-month assessment (0.62; 0.49), and moderate in the 12-month assessment (0.74).

CONCLUSION

: Climbing up stairs should be assessed at intervals of nine months or longer, when responsiveness is moderate to high. Going down stairs should be assessed annually because moderate responsiveness was observed in this period.

摘要

目的

在一项为期一年的随访研究中,确定杜氏肌营养不良功能评估量表(FES-DMD-D3)中上下楼梯领域的反应能力。

方法

本研究纳入了 26 名 DMD 患者。效应量(ES)和标准化反应均值(SRM)描述了量表的反应能力。

结果

上楼梯方面,ES 显示,在三个月评估时反应能力较低(0.26;0.35;0.13;0.17),在六个月评估时为低至中度(0.58;0.48;0.33),在九个月评估时为中度(0.70;0.68),在十二个月评估时为高度(0.88)。SRM 显示,在三个月评估时反应能力较低(0.29;0.38;0.18;0.19),在六个月评估时为低至中度(0.59;0.51;0.36),在九个月评估时为中度(0.74 和 0.70),在十二个月评估时为高度(0.89)。下楼梯方面,ES 显示,在三个月和六个月评估时反应能力较低(0.16;0.25;0.09;0.08 和 0.48;0.35;0.18),在九个月评估时为低至中度(0.59;0.44),在十二个月评估时为中度(0.71)。SRM 显示,在三个月和六个月评估时反应能力较低(0.25;0.35;0.12;0.09 和 0.47;0.38;0.21),在九个月评估时为低至中度(0.62;0.49),在十二个月评估时为中度(0.74)。

结论

上楼梯应每九个月或更长时间评估一次,此时反应能力为中等到高度。下楼梯应每年评估一次,因为在此期间观察到中度反应能力。

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