Nicander I, Nyren M, Emtestam L, Ollmar S
Center for Oral Biology, Karolinska Institute, NOVUMdepartment of Dermatology, Huddinge University Hospital, Huddinge, Sweden.
Skin Res Technol. 1997 Nov;3(4):252-8. doi: 10.1111/j.1600-0846.1997.tb00194.x.
BACKGROUND/AIMS: During previous studies on the electrical impedance of the skin, we formulated a set of four physical indices that could be used to distinguish between the cutaneous effects produced by different chemical irritants. We now employ the electrical impedance technique to compare the properties of different anatomical areas of the skin, using the same set of indices.
Investigations were performed on 131 healthy volunteers, who were divided into four groups on the basis of age and sex. Readings of electrical impedance were taken from ten different regions over the body, and transepidermal water loss was measured for comparison.
Baseline values of electrical impedance of the skin were shown to vary, depending on the site. Age was also found to exert a major influence, causing an increase in the indices related to magnitude (MIX, RIX, and IMIX) with increasing age, and a decrease in that related to phase (PIX), while sex had only a marginal effect.
As with other non-invasive techniques, baseline characteristics differ from place to place over the body surface, and age is another important determining factor.
背景/目的：在之前关于皮肤电阻抗的研究中，我们制定了一组四个物理指标，可用于区分不同化学刺激物产生的皮肤效应。现在，我们使用相同的指标集，采用电阻抗技术来比较皮肤不同解剖区域的特性。
对131名健康志愿者进行了调查，根据年龄和性别将他们分为四组。从身体上十个不同区域读取电阻抗读数，并测量经表皮水分流失以作比较。
皮肤电阻抗的基线值显示因部位而异。还发现年龄有重大影响，随着年龄增长，与幅度相关的指标（MIX、RIX和IMIX）增加，与相位相关的指标（PIX）下降，而性别只有轻微影响。
与其他非侵入性技术一样，体表不同部位的基线特征各不相同，年龄是另一个重要的决定因素。
