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美国应对严重传染病的准备:埃博拉病毒疫情给我们的教训。

Preparing for Serious Communicable Diseases in the United States: What the Ebola Virus Epidemic Has Taught Us.

机构信息

Emory University School of Medicine, Atlanta, GA 30307.

出版信息

Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.EI10-0011-2016.

DOI:10.1128/microbiolspec.EI10-0011-2016
PMID:27337477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4922497/
Abstract

Ending the West Africa Ebola virus disease (EVD) outbreak required an unprecedented international response. For the United States, participation in the international response to the West Africa EVD outbreak provided an opportunity to learn important lessons in four key domains critical to preparing for future outbreaks of EVD and other serious communicable diseases: (i) safe and effective patient care, (ii) the role of experimental therapeutics and vaccines, (iii) infection control, and (iv) hospital and community preparedness.

摘要

结束西非埃博拉病毒病(EVD)疫情需要采取前所未有的国际应对措施。对美国而言,参与西非埃博拉疫情的国际应对为其提供了一个机会,使其能够吸取在为埃博拉等严重传染病疫情做准备的四个关键领域中的重要经验教训:(一)安全有效的病患护理;(二)实验性治疗方法和疫苗的作用;(三)感染控制;以及(四)医院和社区的准备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3af/4922497/f8d6a2ed0337/nihms-758102-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3af/4922497/f8d6a2ed0337/nihms-758102-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3af/4922497/f8d6a2ed0337/nihms-758102-f0001.jpg

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本文引用的文献

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Molecular Evidence of Sexual Transmission of Ebola Virus.埃博拉病毒性传播的分子证据
N Engl J Med. 2015 Dec 17;373(25):2448-54. doi: 10.1056/NEJMoa1509773. Epub 2015 Oct 14.
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Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.rVSV- 载体疫苗表达埃博拉表面糖蛋白的功效和效果:来自几内亚环疫苗接种群组随机对照试验的中期结果。
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Creating a Global Health Risk Framework.
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Critical Care for Multiple Organ Failure Secondary to Ebola Virus Disease in the United States.美国埃博拉病毒病继发多器官功能衰竭的重症监护
Crit Care Med. 2015 Oct;43(10):2066-75. doi: 10.1097/CCM.0000000000001197.
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Ebola virus disease: preparedness and infection control lessons learned from two biocontainment units.埃博拉病毒病:从两个生物安全隔离单位吸取的防范和感染控制经验教训
Curr Opin Infect Dis. 2015 Aug;28(4):343-8. doi: 10.1097/QCO.0000000000000176.
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Development of experimental and early investigational drugs for the treatment of Ebola virus infections.用于治疗埃博拉病毒感染的实验性和早期研究性药物的研发。
Expert Opin Investig Drugs. 2015;24(8):999-1011. doi: 10.1517/13543784.2015.1052403. Epub 2015 Jun 12.
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Persistence of Ebola Virus in Ocular Fluid during Convalescence.埃博拉病毒在康复期眼液中的持续存在。
N Engl J Med. 2015 Jun 18;372(25):2423-7. doi: 10.1056/NEJMoa1500306. Epub 2015 May 7.
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Environmental infection control considerations for Ebola.埃博拉的环境感染控制考量
Am J Infect Control. 2015 Jul 1;43(7):747-9. doi: 10.1016/j.ajic.2015.03.006. Epub 2015 Apr 29.
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Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study.乌干达邦迪布焦埃博拉病毒病的长期后遗症:一项回顾性队列研究。
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The Use of TKM-100802 and Convalescent Plasma in 2 Patients With Ebola Virus Disease in the United States.TKM-100802和恢复期血浆在美国2例埃博拉病毒病患者中的应用
Clin Infect Dis. 2015 Aug 15;61(4):496-502. doi: 10.1093/cid/civ334. Epub 2015 Apr 22.