通过金属卡宾插入实现C(sp(3))-H键官能团化的最新进展。
Recent advances in C(sp(3))-H bond functionalization via metal-carbene insertions.
作者信息
Wang Bo, Qiu Di, Zhang Yan, Wang Jianbo
机构信息
Beijing National Laboratory of Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.
出版信息
Beilstein J Org Chem. 2016 Apr 25;12:796-804. doi: 10.3762/bjoc.12.78. eCollection 2016.
The recent development of intermolecular C-H insertion in the application of C(sp(3))-H bond functionalizations, especially for light alkanes, is reviewed. The challenging problem of regioselectivity in C-H bond insertions has been tackled by the use of sterically bulky metal catalysts, such as metal porphyrins and silver(I) complexes. In some cases, high regioselectivity and enantioselectivity have been achieved in the C-H bond insertion of small alkanes. This review highlights the most recent accomplishments in this field.
本文综述了分子间C-H插入在C(sp(3))-H键官能团化应用中的最新进展，特别是在轻质烷烃方面。通过使用空间位阻较大的金属催化剂，如金属卟啉和银(I)配合物，解决了C-H键插入中区域选择性这一具有挑战性的问题。在某些情况下，小烷烃的C-H键插入已实现了高区域选择性和对映选择性。本综述重点介绍了该领域的最新成果。
Zotero 插件