Furlong Kayla R, Anderson Laura N, Kang Huiying, Lebovic Gerald, Parkin Patricia C, Maguire Jonathon L, O'Connor Deborah L, Birken Catherine S
Child Health and Evaluative Sciences, Research Institute, and.
Child Health and Evaluative Sciences, Research Institute, and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada;
Pediatrics. 2016 Jul;138(1). doi: 10.1542/peds.2015-3809.
To determine the agreement between weight-for-length and BMI-for-age in children 0 to <2 years by using research-collected data, examine factors that may affect agreement, and determine if agreement differs between research- and routinely collected data.
Cross-sectional data on healthy, term-born children (n = 1632) aged 0 to <2 years attending the TARGet Kids! practice-based research network in Toronto, Canada (December 2008-October 2014) were collected. Multiple visits for each child were included. Length (cm) and weight (kg) measurements were obtained by trained research assistants during research visits, and by nonresearch staff during all other visits. BMI-for-age z-scores were compared with weight-for-length z-scores (the criterion measure).
The correlation between weight-for-length and BMI-for-age was strong (r = 0.986, P < .0001) and Bland-Altman plots revealed good agreement (difference = -0.08, SD = 0.20, P = .91). A small proportion (6.3%) of observations were misclassified and most misclassifications occurred near the percentile cutoffs. There were no differences by age and sex. Agreement was similar between research- and routinely collected data (r = 0.99, P < .001; mean difference -0.84, SD = 0.20, P = .67).
Weight-for-length and BMI-for-age demonstrated high agreement with low misclassification. BMI-for-age may be an appropriate indicator of growth in the first 2 years of life and has the potential to be used from birth to adulthood. Additional investigation is needed to determine if BMI-for-age in children <2 years is associated with future health outcomes.
利用研究收集的数据确定0至不满2岁儿童身长别体重与年龄别BMI之间的一致性,检查可能影响一致性的因素,并确定研究收集的数据与常规收集的数据之间的一致性是否存在差异。
收集了加拿大多伦多参加“目标儿童”基于实践的研究网络(2008年12月至2014年10月)的0至不满2岁健康足月儿(n = 1632)的横断面数据。纳入了每个儿童的多次访视。在研究访视期间,由经过培训的研究助理测量身长(厘米)和体重(千克),在所有其他访视期间由非研究人员测量。将年龄别BMI z评分与身长别体重z评分(标准测量指标)进行比较。
身长别体重与年龄别BMI之间的相关性很强(r = 0.986,P <.0001),Bland-Altman图显示一致性良好(差异=-0.08,标准差= 0.20,P =.91)。一小部分(6.3%)观察结果被错误分类,大多数错误分类发生在百分位数切点附近。按年龄和性别无差异。研究收集的数据与常规收集的数据之间的一致性相似(r = 0.99,P <.001;平均差异-0.84,标准差= 0.20,P =.67)。
身长别体重与年龄别BMI显示出高度一致性且错误分类率低。年龄别BMI可能是生命最初2年生长的合适指标,并且有可能从出生到成年期使用。需要进一步调查以确定2岁以下儿童的年龄别BMI是否与未来健康结果相关。