Kanehira Yuka, Kawakami Susumu, Sugimoto Sachiko, Matsunami Katsuyoshi, Otsuka Hideaki
Department of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
Department of Natural Product Chemistry, Faculty of Pharmacy, Yasuda Women's University, 6-13-1 Yasuhigashi, Asaminami-ku, Hiroshima, 731-0153, Japan.
J Nat Med. 2016 Oct;70(4):816-24. doi: 10.1007/s11418-016-1019-8. Epub 2016 Jun 28.
Extensive isolation work on the 1-BuOH-soluble fraction of a MeOH extract of the aerial parts of Dianthus japonicus afforded three further triterpene glycosyl estsers, termed dianthosaponins G-I, an anthranilic acid amide glucoside and a C-glycosyl flavonoid along with one known triterpene saponin. Their structures were elucidated from spectroscopic evidence. The cytotoxicity of the isolated compounds toward A549 cells was evaluated.
对日本石竹地上部分甲醇提取物的正丁醇可溶部分进行了广泛的分离工作,得到了另外三种三萜糖苷酯,即石竹皂苷G - I、一种邻氨基苯甲酸酰胺葡萄糖苷和一种C - 糖基黄酮,以及一种已知的三萜皂苷。通过光谱证据阐明了它们的结构。评估了分离出的化合物对A549细胞的细胞毒性。