State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, People's Republic of China.
Department of Chemistry, School of Science and MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiaotong University , Xi'an 710049, China.
Org Lett. 2016 Jul 15;18(14):3486-9. doi: 10.1021/acs.orglett.6b01702. Epub 2016 Jun 29.
A new method for the AgSCF3-mediated radical cascade difunctionalizing trifluoromethythiolation of alkynes with dearomatization is developed. This protocol provides a novel route to SCF3-substituted spirocyclic compounds via the formation of one C-SCF3 bond, one C-C bond, and one C-O double bond in a single step.
发展了一种新的方法，用于 AgSCF3 介导的炔烃的自由基级联双官能化三氟甲硫基化反应，同时实现去芳构化。该方案通过一步反应形成一个 C-SCF3 键、一个 C-C 键和一个 C-O 双键，为 SCF3 取代的螺环化合物提供了一条新途径。
