Verspoor Floortje G M, Hannink Gerjon, Scholte Anouk, Van Der Geest Ingrid C M, Schreuder H W Bart
a Department of Orthopedics , Radboud University Medical Center , Nijmegen , the Netherlands.
Acta Orthop. 2016 Oct;87(5):497-503. doi: 10.1080/17453674.2016.1205168. Epub 2016 Jun 30.
Background and purpose - Tenosynovial giant cell tumors (t-GCTs) can behave aggressively locally and affect joint function and quality of life. The role of arthroplasty in the treatment of t-GCT is uncertain. We report the results of arthroplasty in t-GCT patients. Patients and methods - t-GCT patients (12 knee, 5 hip) received an arthroplasty between 1985 and 2015. Indication for arthroplasty, recurrences, complications, quality of life, and functional scores were evaluated after a mean follow-up time of 5.5 (0.2-15) years. Results - 2 patients had recurrent disease. 2 other patients had implant loosening. Functional scores showed poor results in almost half of the knee patients. 4 of the hip patients scored excellent and 1 scored fair. Quality of life was reduced in 1 or more subscales for 2 hip patients and for 5 knee patients. Interpretation - In t-GCT patients with extensive disease or osteoarthritis, joint arthroplasty is an additional treatment option. However, recurrences, implant loosening, and other complications do occur, even after several years.
背景与目的——腱鞘巨细胞瘤(t-GCTs)可在局部呈侵袭性生长,影响关节功能和生活质量。关节置换术在t-GCT治疗中的作用尚不确定。我们报告了t-GCT患者接受关节置换术的结果。
患者与方法——1985年至2015年间,t-GCT患者(12例膝关节,5例髋关节)接受了关节置换术。在平均随访5.5(0.2 - 15)年后,评估关节置换术的指征、复发情况、并发症、生活质量和功能评分。
结果——2例患者疾病复发。另外2例患者出现植入物松动。几乎一半的膝关节患者功能评分结果较差。5例髋关节患者中4例评分优秀,1例评分中等。2例髋关节患者和5例膝关节患者在1个或更多子量表中的生活质量有所下降。
解读——对于患有广泛性疾病或骨关节炎的t-GCT患者,关节置换术是一种额外的治疗选择。然而,即使在数年之后,复发、植入物松动和其他并发症确实会发生。